Alcohol flush reaction -- the technical term for experiencing a flushed reaction after drinking alcohol -- occurs in people with inactive aldehyde dehydrogenase 2 enzyme, which is responsible for breaking down acetaldehyde, the byproduct of metabolized alcohol. Without ALDH2, acetaldehyde accumulates in the body, causing flushing. Though it is not possible to replace ALDH2, you can prevent alcohol flush reaction by changing your drinking habits.
Step 1
Eat a meal prior to drinking alcohol. This will slow the metabolism of alcohol, thereby reducing the buildup of acetaldehyde and preventing the alcohol flush reaction.
Step 2
Drink alcohol slowly, no faster than one drink per hour. Drinking slowly allows your body to flush out the acetaldehyde, instead of allowing it to accumulate and cause red flush.
Step 3
Take a histamine H2-receptor antagonist, such as ranitidine, cimetidine or famotidine. According to "Focus on Nursing Pharmacology," these over-the-counter medications block the body's response to acetaldehyde. As a result, the alcohol flush reaction is reduced.
References
- "Foundations of Nursing"; Lois White et al; 2010
- "Nutrition: Concepts and Controversies"; Frances Sizer; 2008
- "Focus on Nursing Pharmacology"; Amy Morrison Karch; 2009
