Compazine is a medication used to treat severe nausea and vomiting. Additional uses for Compazine include treating psychotic disorders such as schizophrenia. The medication is available with a physician's prescription and comes in several dosing options, which include oral, intravenous and rectal routes. As with any medication, there are some potential side effects from taking this drug.
Common Side Effects
Common side effects associated with taking Compazine include increased sweating, a sensitivity to cold temperatures, sensitivity to sunlight and skin rashes. The urine may appear darker after taking Compazine. Symptoms such as dry mouth, nausea, constipation, blurred vision, muscle stiffness, abdominal pain and agitation may occur after taking Compazine. Dizziness and an increase in drowsiness are common side effects from this medication. Headaches are common after taking a dose.
Serious Side Effects
One potential side effect from Compazine includes neuroleptic malignant syndrome (NMS). This condition causes a fever, muscle stiffness, loss of bladder control, labored breathing and an increased heart rate. According to the Mayo Clinic, Compazine may cause a painful, prolonged penile erection. This condition warrants immediate medical attention to prevent permanent damage. Fainting may occur after taking this antipsychotic medicine. Vision changes such as blurry vision, a decrease in night vision and changes in color perception may occur.
Extrapyramidal Reactions
Tardive dyskinesia is a syndrome associated with taking some antipsychotic medications such as Compazine. The condition causes an individual to have repetitive, rhythmic movements of the body. The areas of the body most affected are the tongue and jaw. An individual with tardive dyskinesia may move the jaw in an unusual manner, thrust the tongue from the mouth or appear to be chewing. Dystonias may also occur and are characterized by rigid back muscles, difficulty swallowing and a shuffling gait. The condition worsens with continued use of the medicine and may be permanent, even after stopping the Compazine. There are no known treatment options for this condition.



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