The Side Effects of Topamax for Migraines

Topamax is a prescription medication used to prevent seizures in patients with epilepsy. Also prescribed for migraine sufferers, it may help decrease the number of migraines experienced. The drug is not a pain reliever, though it can be taken with pain medications when a migraine strikes. Side effects include metabolic acidosis, vision changes, kidney stones and suicidal thought or behaviors. Talk to your doctor about the potential side effects before use.

Metabolic Acidosis

Topamax can cause a potentially serious condition called metabolic acidosis (an increase of acid in the blood), according to the PDR Health. Symptoms of this condition include rapid breathing, confusion, irregular heartbeat, lethargy, fatigue and loss of appetite.

Vision Changes

Changes in vision are possible with the use of Topamax. Severe nearsightedness and increased pressure inside the eye can occur, typically within the first month of use. According to PDR Health, those with these symptoms should let their doctor know immediately, as permanent vision loss could occur with continued use.

Kidney Stones

Kidney stones, solid masses (crystals) that form in the kidneys, can develop with the use of Topamax for migraines. Kidney stones may be present without symptoms or cause the flow of urine to be blocked, causing pain and swelling of the kidneys.

Suicidal Thoughts/ Behaviors

Some individuals become depressed or suicidal while using Topamax for migraines. According to Medline Plus, approximately one out of every 500 people who took Topamax became suicidal during treatment. Adverse thoughts and behaviors may occur within a week of use. Talk to your doctor if you notice these changes.

Other Side Effects

Other, less serious side effects can result from the use of Topamax for migraines. Mental changes that include trouble finding words, confusion or slowed thinking can occur with treatment. Other side effects such as weight loss, tingling in the hands or feet, dry mouth and decreased sweating may also result. Decreased sweating can lead to increased body temperature, causing overheating and increasing the risk of heat stroke. In addition, hot baths or saunas may make you dizzy, according to the Mayo Clinic.

References

Last updated on: Dec 1, 2009

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