Ascorbic acid, also known as vitamin C, is a water soluble vitamin that has antioxidant properties. It helps reduce free radical production that is associated with disease and illness. In addition, research indicates that vitamin C might have anti-inflammatory effects. Consult your health care provider before taking any vitamin C supplements.
C-reactive Protein
Researchers from the University of California Berkeley investigated the effects of vitamin C on C-reactive protein, an inflammatory marker associated with heart disease. Healthy subjects consumed 1,000 mg of vitamin C or a placebo for two months. C-reactive protein was measured before and after the experiment. They reported in the September 2008 issue of the journal "Free Radical Biology & Medicine" that vitamin C lowered C-reactive protein levels in patients with elevated C-reactive protein levels, but not in patients with normal C-reactive protein levels.
Interleukin-6 and Exercise
Scientists from the Copenhagen Muscle Research Centre in Denmark studied the impact of vitamins C and E on interleukin-6, a protein that increases inflammation when muscles contract. Participants were assigned 500 mg of vitamin C and 400 international units of vitamin E or a placebo for 28 days. Afterward, subjects underwent resistance training. Interleukin-6 was measured before and after supplementation. Researchers found that vitamin C and E supplementation blunted the normal increases in interleukin-6 associated with weight training compared to the placebo. Their findings were published in the July 2004 issue of the "Journal of Physiology."
Vitamin C Intake
In research published in the March 2006 issue of the "American Journal of Clinical Nutrition," researchers from Royal Free and University College Medical School explored the relationship between vitamin C status and inflammation. They discovered that people with the highest intakes of vitamin C had lower levels of C-reactive protein compared to those with the lowest intakes.
Interactions
Vitamin C may interact with several medications, including nonsteroidal anti-inflammatory drugs, aspirin, acetaminophen and antacids, according to the University of Maryland Medical Center. Therefore, consult your health care provider before taking any vitamin C supplements, especially if you are on medication.
References
- "Free Radical Biology & Medicine;" Vitamin C Treatment Reduces Elevated C-reactive Protein; G. Block, et al.; September 2008
- "Journal of Physiology;" Supplementation with Vitamins C and E Inhibits the Release of Interleukin-6 From Contracting Human Skeletal Muscle; C.P. Fischer, et al.; July 2004
- "American Journal of Clinical Nutrition;" Associations of Vitamin C Status, Fruit and Vegetable Intakes, and Markers of Inflammation and Hemostasis; S.G. Wannamethee, et al.; March 2006
- University of Maryland Medical Center: Vitamin C



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