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Stomach Pain After Taking Naproxen Sodium

author image Helen Messina
Helen Messina started writing in 2010. She is a registered nurse with experience in rehabilitation, long-term/subacute care, pediatric/adult home care and has worked in acute care facilities in Florida, Pennsylvania, New Jersey and New York. Messina's specialties include neurology, cardiac and renal care. She holds an associate degree in nursing from Gannon University.
Stomach Pain After Taking Naproxen Sodium
Stomach pain while taking naproxen might indicate a serious gastrointestinal problem. Photo Credit Stomach ache image by Hedgehog from <a href="http://www.fotolia.com">Fotolia.com</a>

Naproxen sodium can temporarily reduce pain and lower your fever, but it can have serious gastrointestinal side effects. Naproxen is grouped with other nonsteroidal anti-inflammatory drugs called NSAIDs, such as aspirin and ibuprofen. Naproxen effectively treats minor aches and pains, especially when taken precisely as prescribed or according to the over-the-counter naproxen label directions. If you have on-going stomach problems, such as stomach upset, pain, heartburn or ulcers, consult your physician before starting naproxen.

Stomach Pain

Stomach pain associated with taking naproxen sodium may indicate serious life-threatening side effects or a possible overdose. A connection exists between taking naproxen and the formation of ulcers in the lining of the stomach, stomach and intestinal bleeding, and perforation of the stomach or intestines, according to Medline Plus. These disorders of the gastrointestinal tract may take place with or without warning symptoms while taking naproxen. Increased risk factors include a history of ulcers, bleeding, being 60 or older, and consumption of steroids, anticoagulants, other NSAIDS and alcohol. Consult your physician immediately if you experience stomach pain with naproxen.

Naproxen Sodium Function

Naproxen sodium, the primary active ingredient in naproxen, is available by prescription and over the counter. It acts by reducing levels of the hormones that create the inflammatory and pain process in the body, a normal response to illness or injury. It is useful in the temporary treatment of conditions such as arthritis, tendinitis, gout, menstrual cramping, muscle aches and pain, backache and headache, common cold symptoms and fever reduction. Naproxen is available in a number of forms such as tablets, liquid and suppositories, as well as in extended-release and controlled-release. Taking naproxen with food or milk may prevent stomach upset.

Side Effects

Common side effects of naproxen sodium include headache, edema, vision problems, constipation, rash, diarrhea and ringing in the ears. Taking naproxen for fevers or for its anti-inflammatory properties may actually mask signs and symptoms of a more serious infection. Naproxen can affect some blood test results, such as liver enzymes, potassium and kidney function. Serious side effects include dizziness, faintness, bloody vomit and bloody, black or tarry stools. These indicate stomach and intestinal bleeding.


Unless specifically ordered by your physician, use of naproxen during the last trimester of pregnancy is discouraged. It may lead to birth defects as well as complications during delivery. Naproxen passes into breast milk, so Drugs.com recommends that you not take it while nursing. Taking more naproxen than prescribed or for longer than prescribed increases the risk of serious cardiovascular problems such as heart attack or stroke. Symptoms associated with the heart and circulation include difficulties with vision or balance, breathing problems, weakness, chest pain and slurred speech.

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