Tyrosine for Restless Leg Syndrome

Tyrosine is a complex amino acid that creates neurotransmitters that govern the nerves. A researcher from Penn State University, James R. Connor, Ph.D., believes there may be a correlation between this amino acid and restless leg syndrome, a neurological condition. If you suffer from restless leg syndrome, talk to your doctor about lifestyle changes and medication that can help.

Restless Leg Syndrome

Restless leg syndrome, or RLS, is a neurological disorder that leads to irritation of the nerves in the lower limbs. The exact cause is elusive, but several factors may contribute to it. One theory is that RLS may be genetic, as researchers have seen a trend in the development of the problem in families for about half the reported cases. The linking factor between tyrosine and RLS is the chemical dopamine.

Dopamine

Dopamine is a chemical released to control muscle movement. The messaging system in the human body consists of a network of nerves. When you need to move your legs, the brain releases a series of chemicals along this network to instruct the muscles to move. RLS may originate in the production of dopamine. During his study, neurologist Connor found that individuals suffering from RLS had low levels of dopamine and high amounts of tyrosine.

Tyrosine

Tyrosine combines with other elements to form other substances. To form dopamine, tyrosine blends with iron. Conner believes that symptoms of RLS appear when the levels of tyrosine exceed the available amounts of iron. If you think of dopamine creation as a recipe, it would be similar to baking cookies after running out of sugar. Excess tyrosine builds up in the brain because no iron is available to use it up.

Considerations

Connor's take on restless leg syndrome remains unproven. He admits that treatment options will vary. If the condition runs in the family, the patient may require a different treatment. Taking iron supplements is not necessary for most individuals, and too much iron in your body can lead to poisoning. In addition, there is no evidence that taking supplemental iron or tyrosine will fix restless leg syndrome. The most appropriate option at this point is to treat the symptoms. Avoid triggers, such as caffeine, smoking and antihistamines. Get regular exercise, and stretch your legs at night. A hot or cool bath may help ease the nervousness in your legs. Finally, your doctor may be able to recommend medication that can help control the symptoms.

References

Article reviewed by Paula Martinac Last updated on: Apr 27, 2011

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