Parkinson's disease is a progressive neurological disorder that occurs when brain cells that produce a chemical called dopamine start to die off. Dopamine is a neurotransmitter that carries messages related to movement. As a result, people with Parkinson's disease often experience tremors, muscle stiffness and movement problems. Other symptoms may include memory loss and dementia. Parkinson's disease is incurable, although there are a number of medicines available that help slow its progression and alleviate symptoms. Folic aid may play a role in the treatment of Parkinson's, but scientific studies evaluating its effects are lacking. Don't take folic acid in place of your Parkinson's medicines and get medical advice before using it.
Properties and Potential Benefits
Folic acid is a synthetic form of folate, a water-soluble B vitamin that is found in foods such as leafy green vegetables, eggs, liver and potatoes. Folic acid supplements are primarily used to prevent neural tube birth defects, but the Memorial Sloan-Kettering Cancer Center notes that it might also play a role in the prevention of cardiovascular disorders and chronic fatigue syndrome. It might also improve cognitive function in adults.
Administration
Folic acid is available in capsules and tablets. Guidance regarding the amount required to support Parkinson's treatment is lacking, although your doctor may be able to advise you. Ensure you take your supplement as directed by your doctor and read the label on your folic acid supplement carefully before using.
Effects
Few studies have evaluated the role of folic acid in the treatment of Parkinson's disease so it is difficult to categorically state that it is beneficial for patients with this condition. However, the Cleveland Clinic Foundation notes that folic acid may be beneficial for patients taking the anti-Parkinson's drug levodopa because it might counteract the damaging effects this drug has on the lining of the body's blood vessels.
Safety Considerations
The Office of Dietary Supplements notes that folic acid intake should not exceed 1,000 micrograms daily. Taking more than this may cause vitamin B12 deficiency, which in turn may lead to nerve damage. The Office of Dietary Supplements adds that high levels of folic acid may trigger seizures in patients taking anti-convulsant medications. Talk to your doctor before taking folic acid, and stop using it if you experience any unusual effects.
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