Vytorin, generically sold as ezetimibe and simvastatin, is a medication used to treat high cholesterol. Cholesterol is composed of high-density lipoprotein (HDL) (good cholesterol) and low-density lipoprotein (LDL) (bad cholesterol). According to Drugs.com, Vytorin lowers your LDL and increases your HDL. When your good cholesterol is increased and your bad cholesterol is decreased, your risk of atherosclerosis (hardening of your arteries), heart attack and stroke decrease dramatically. Take charge of your health and learn about Vytorin's side effects.
Myopathy and Rhabdomyolysis
Vytorin can detrimentally affect your muscles and cause extreme pain. Because Vytorin is a combination of simvastatin and ezetimibe, it inherits each of its side effects. The simvastatin component of Vytorin leads to myopathy (muscle damage) when your creatine kinase (substance released from your muscles during damage) results in levels ten times greater than the upper limit of normal (ULN), states RxList.com. Myopathy symptoms include muscle tenderness, pain and weakness. When myopathy worsens, it can transform into rhabdomyolysis (condition of muscle breakdown). Tell your doctor whether you experience muscle pain with Vytorin for find a safer medication for you.
Mild Side Effects
According to Drugs.com, Vytorin's mild side effects include constipation or diarrhea, trouble sleeping, back pain or numbness and tingling. Vytorin can affect your psyche and lead to memory problems and depression. In some instances, you may also develop headaches, joint pain, cough or a sore throat.
Physical Side Effects
Vytorin can irritate your stomach and lead to stomach pain, indigestion, flatulence (gas) or gastritis (stomach infection). Users may also develop diabetes mellitis (high blood sugar levels) and infections such as sinusitus (sinus infection), bronchitis (respiratory infection) or urinary tract infections (kidney infection). Vytorin is also associated with increases in your liver enzymes (substance produced in your liver that allows you to measure its function). If you have these problems, seek help immediately.
Allergic Reaction
Stop taking Vytorin if you find yourself allergic to its ingredients. Signs of an allergic reaction include trouble breathing, hives and swelling of your face, lips or throat. Seek immediate help to reverse these harmful side effects.



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