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Grapeseed Oil for High Cholesterol

May 4, 2011 | By Joanne Marie

Cholesterol is a type of fat found in your blood, where it is combined with protein to form a compound called a lipoprotein. Cholesterol is needed by your cells to build cellular membranes and for many biochemical reactions. However, when cholesterol levels are too high, your risk for cardiovascular disease, heart attach and stroke is increased. Grapeseed oil is a traditional remedy that may help keep your cholesterol level in a healthy range. Consult your doctor to discuss consuming grapeseed oil before adding it to your regimen.

LDL and HDL

Two types of lipoprotein carry cholesterol in your blood, low-density lipoprotein, or LDL, and high-density lipoprotein, or HDL. LDL is called "bad" cholesterol because it may form deposits, or plaque, on your arterial walls, potentially interfering with blood flow and causing cardiovascular disease. HDL is called "good" cholesterol because it carries excess cholesterol to your liver, removing it from your blood. Grapeseed oil has several properties that may help reduce your level of LDL.

Grapeseed Oil

Grapeseed oil, also called grapeseed extract or GSE, is a byproduct of wine making. The seeds of the grapes are separated from the pulp and ground to make an oil, which has been used medicinally for many years. It is traditionally consumed for gastric problems, to relieve constipation or to promote bile production. Grapeseed oil is also used topically to treat burns and other skin irritations. The oil contains a natural chemical called proanthocyanidin, which is a powerful antioxidant that may help reduce levels of LDL.

The Evidence

Several laboratory studies suggest that grapeseed oil may effectively lower levels of LDL in the blood. In one study, published in "Cardiovascular Pathology" in 2010, grapeseed oil protected animals against high cholesterol induced by diet, compared to other animals that did not consume the oil. Several small clinical studies have also been carried out with human subjects. In a study published in "Journal of Medicine" in 2000, subjects with high cholesterol who consumed a mixture of chromium and grapeseed extract experienced a significant drop both total cholesterol and LDL, compared to others who took a placebo. These results are very promising, although larger studies with human subjects are still needed.

Recommendations and Precautions

Grapeseed oil is available from most health food stores, usually standardized for its content of proanthocyanidin. A recommended dose is 25 to 150 mg, up to three times daily. The supplement is generally considered safe and without significant side effects. However, do not take grapeseed oil if you are pregnant or breastfeeding, or if you take blood thinning medications. Talk to your doctor to determine if grapeseed oil is a good choice for you.

References

Article reviewed by Jenna Marie Last updated on: May 4, 2011

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