Coenzyme Q10 plays a central role in energy production and also functions as an antioxidant. Touted for a variety of purposes, it is probably best known to improve heart health, and according to the University of Maryland Medical Center, research indicates it might help boost heart function, reduce heart damage and lower blood pressure among other benefits. Suggested dosages have been established but the optimal dose will depend on your reason for using CoQ10 and other individual factors. You should consult with your doctor for guidance on the proper dosage and other aspects of safe usage.
Suggested Dosage
UMMC reports the standard daily dosage for CoQ10 ranges fro 30 mg to 200 mg daily. Medline Plus, a site operated by the National Library of Medicine, notes some research-based suggested dosages for various conditions, with some exceeding the aforementioned general dosage by quite a bit. This underscores the importance of seeking professional guidance. If a deficiency has been established, you should take 150 mg daily. You will need between 100 mg and 300 mg daily for heart failure, reducing the risk of future heart attack, high blood pressure, preventing migraines and male infertility. Certain conditions, such as Parkinson's disease and mitochondrial disorders might require 2,400 mg to 3,000 mg daily.
Optimizing Absorption
Your body will better absorb CoQ10 in the form of gel capsules. Take supplements with a full glass of water and a meal containing some fat for optimal absorption. Taking CoQ10 at night might also aid in better absorption.
Drug Interactions
According to Drugs.com, a site that compiles information from various medical databases, CoQ10 could potentially interact with beta-blockers -- used to treat high blood pressure, blood-thinning medications like warfarin and diabetes medications. Medline Plus reports it might also interfere with chemotherapy medications, making them less effective.
Other Considerations
Whether or not you can safely use this supplement during pregnancy or breastfeeding has not been established. Potential side effects include stomach upset, loss of appetite and nausea -- taking CoQ10 in divided doses can reduce these effects. Discontinue use at least two weeks before surgery as this supplement might interfere with blood pressure control during the procedure.
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