The mineral chromium picolinate performs various functions in the body, including the regulation of blood sugar. For the most part, you will not need supplementation to ensure your body has enough for these tasks since it only requires small amounts. In certain instances, however, you might require a supplement to achieve a therapeutic effect, such as lowering blood sugar if you have diabetes. Chromium has also been touted for other purposes, including weight loss and building muscle mass, but research indicates mixed results for these purposes. Most chromium supplements come in the form of chromium picolin, and some dosage guidelines have been established. Consult with your physician before using chromium supplements. Higher doses have been associated with potentially serious side effects.
Recommended Dosage
According to Drugs.com, scientific studies looking at the effects of chromium picolinate on various conditions typically used dosages ranging from 200 mcg to 1,000 mcg daily. The University of Maryland Medical Center says a standard dosage typically consists of 200 mcg one to three times a day. Diabetics in particular might benefit from the higher-range dose of 1,000 mcg daily, but the long-term effects of amounts that high have not been established. The recommended dosages for therapeutic purposes far exceed the amount you need to require to avoid deficiency -- which can range from only 20 mcg to 35 mcg daily for adults, depending on age and gender. For this reason, you should seek guidance from your doctor for the dosage appropriate for your condition.
Medication Interactions
Because of chromium's potential to lower blood sugar, using it at the same time as insulin or other drugs that control blood sugar could induce hypoglycemia. If you want to experiment with chromium to control your glucose levels, consult with your doctor who can monitor your treatment plan and make adjustments to your medication dosages to compensate for the effects of chromium. According to the UMMC, studies of diabetics using chromium found they did in fact require such changes. Only your doctor can safely make this determination.
Use in Certain Populations
Whether or not you can safely use chromium picolinate while pregnant or breastfeeding has not been established. Drugs.com says animal studies have shown chromium picolinate supplementation caused skeletal and neurological problems in babies of mice give this supplement. While seeking professional guidance is prudent in all cases, you should definitely do so if you have any condition that affects the liver or kidneys. These organs play a central role in processing and breaking down drugs and supplements. While rare, the UMMC notes reports of liver and kidney damage stemming from chromium picolinate use. The University of Pittsburgh Medical Center reports that picolinate could affect the level of neurotransmitters -- chemical messengers that heavily influence mood and behavior -- making use potentially problematic if you suffer from problems like bipolar disorder or depression.
Other Considerations
The UPMC reports that in some instances, high doses of chromium can trigger the conversion of the mineral into a carcinogen -- a substance that can cause cancer. Potential side effects include dermatitis and stomach irritation. When used in doses up to 200 mcg, it appears to pose little risk. If you have a condition such as diabetes, where higher doses have been used, you should not take chromium unsupervised.
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