Fatty liver disease, or steatosis, is the abnormal accumulation of fats, especially triglycerides, in the liver due to excessive alcohol consumption, certain medications, metabolic abnormalities or high blood triglyceride levels. The condition is generally asymptomatic, although abdominal discomfort and fatigue may sometimes occur. Rarely the condition may progress into liver inflammation, scarring in the liver and liver failure. Healthy diet, exercise and avoiding alcohol and medications may help treat the condition. Certain vitamins, such as vitamin E, may also help manage fatty liver disease.
About Vitamin E
Vitamin E is a fat-soluble vitamin that has the ability to stabilize free radicals, which interact with DNA and proteins of healthy cells and damage them. It also plays an important role in the formation of red blood cells. MedlinePlus recommends a dosage of 4 to 15 mg of vitamin E per day, depending on the age and condition of the patient. The vitamin can be obtained from foods such as wheat germ, corn, nuts, seeds, olives and vegetable oils. Natural and synthetic vitamin E supplements are also available at most pharmacies without prescription.
Vitamin E Research
Vitamin E, in combination with vitamin C, is an effective, safe and inexpensive alternative to treat fatty liver disease and may be used in place of medications such as ursodeoxycholic acid, says a study in the September 2005 issue of "The Turkish Journal of Gastroenterology." "Science Daily" also reported in April 2011 that certain forms of vitamin E can help improve the levels of the enzyme alanine aminotransferase in the liver and help treat nonalcoholic fatty liver disease in children. A study in the May 2010 issue of the "New England Journal of Medicine" also suggests that vitamin E can help significantly improve fatty liver disease in nondiabetic adults.
Side Effects
Vitamin E supplements are generally safe to use, although mild allergic reactions, such as rash, hives and shortness of breath, may sometimes occur. MayoClinic.com also warns that regular use of high-dose of vitamin E can increase the risk of death from all causes. In rare cases, supplements can also lead to dizziness, fatigue, blurred vision, headache and loss of kidney function.
Precautions
Seek immediate medical help if you experience allergic reactions to vitamin E supplements. It is important to consult a doctor before using vitamin E supplements to avoid possible drug interactions and adverse reactions. Your doctor may also help you determine the dose and form of the vitamin that is right for you.
References
- MedlinePlus: Vitamin E
- "The Turkish Journal of Gastroenterology"; Management of Fatty Liver Disease with Vitamin E and C Compared to Ursodeoxycholic Acid Treatment; G. Ersöz, et al.; September 2005
- Science Daily: Vitamin E Helps Diminish a Type of Fatty Liver Disease in Children, Study Suggests
- "New England Journal of Medicine"; Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis; Arun J. Sanyal, et al.; May 2010
- Mayo Clinic: Vitamin E
Member Comments