Kudzu has a long history of use in traditional Chinese medicine for treating alcoholism, menopausal symptoms, diabetes and the common cold. The Memorial Sloan-Kettering Cancer Center reports clinical trials show it is effective against menopausal symptoms like hot flashes, night sweats and reduced cognitive function. The University of Pittsburgh Center notes mixed evidence on whether or not it can treat alcoholism. Kudzu appears to be a generally safe herb, but you should consult with a doctor knowledgeable in herbal medicine for guidance on safe usage. Certain circumstances, however, could make use problematic.
Estrogenic Activity
MSKCC reports kudzu has demonstrated estrogenic activity. Avoid this herb if you currently suffer from, have had in the past or have a risk of hormone-sensitive cancers like estrogen-receptor positive breast cancer. It might also interfere with the actions of tamoxifen, a common breast cancer treatment drug.
Allergic Reactions
Allergic reactions have been reported. If taking this herb, watch for signs of an allergic reaction, including swelling, itching, sneezing, rash, watery eyes and trouble breathing.
Use in Specific Populations
Whether or not you can safely use kudzu while pregnant or nursing has not been established, meaning what kind of side effects might result remains unknown. In this instance, avoid use. Safe use in patients with liver or kidney disease has not been determined either. These organs are particularly sensitive to the drugs, herbs and other supplements you consume -- particularly when their function has been impaired -- and you should talk to your doctor before using any treatment, as it could potentially worsen symptoms of these conditions.
Other Potential Negative Effects
Kudzu might lower blood sugar levels; if you take medications to control your blood sugar, you might require dosage adjustments to compensate for the actions of the herb. Only your doctor can determine this. It might also interfere with the actions of the liver enzymes P450 2D6 and P450 1A2; if you take drugs that require these enzymes for metabolism, use of kudzu could potentially produce negative actions such as decreasing effectiveness or increasing the risk of side effects. This underscores the importance of seeking professional guidance before using herbs if you take prescription medications.
