Role of Testosterone Replacement for Osteoporosis

Role of Testosterone Replacement for Osteoporosis
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Osteoporosis currently affects one out of five women in America. While both exercise and nutritional strategies exist to help combat this problem, a little extra help may be necessary from time to time. Testosterone, a steroidal hormone women produce via the adrenal glands, can help improve bone mineral density. Consult your health care provider for advice on integrating testosterone therapy with your diet and exercise program to treat osteoporosis.

Osteoporosis

Osteoporosis is a progressive weakening of the bones secondary to a loss of bone mineral density. While osteoporosis can occur in anyone, it is far more common in women. If you are smaller in stature, older, or have a family history of osteoporosis you are at an increased risk of contracting this condition. Factors that you can control include diet and exercise, as a diet low in calcium, total calories, and vitamin D combined with a lack of weight-bearing exercise increases your risk of osteoporosis.

Testosterone

Testosterone is a hormonal produced by your endocrine system. As a drug, it belongs to the class of compounds known as anabolic-androgenic steroids, or AAS. Testosterone, like all drugs, has multiple effects, including the improvement of strength and lean muscle mass. Testosterone has been used in the treatment of osteoporosis since the 1990s, according to the "The Journal of Clinical Endocrinology and Metabolism." In a 1999 study researchers showed that androgen replacement therapy in women was useful in treating numerous wasting conditions.

Specific Function of Testosterone

As you age, there is a decrease in your production of testosterone. There is also a direct correlation between your decrease in testosterone and your specific bone mineral density, according to researchers at the University of Copenhagen. A study published in the 1987 issue of "The Journal of Clinical Endocrinology and Metabolism" showed that during periods of peak testosterone production, women displayed fewer symptoms of osteoporosis than during periods of lower testosterone production.

Therapy

Testosterone has a marked effect on improvements in bone mineral density. According to a 2006 study published in "The Journal of Clinical Endocrinology and Metabolism," intramuscular injections had a noted effect on improvements in bone mineral density. Androgen use, such as testosterone, is effective in stimulating increases in bone mineral density in women. However, according to a 2006 review of literature published in the "European Journal of Endocrinology," testosterone use in women should only be administered when women show a testosterone deficiency.

References

Article reviewed by David Fisher Last updated on: May 23, 2011

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