Protonix, whose generic name is pantoprazole, is a proton pump inhibitor used to treat erosive esophagitis, gastroesophageal reflux disease, stomach ulcers, duodenal ulcers and Zollinger-Ellison syndrome. Protonix suppresses the secretion of hydrochloric acid by stomach parietal cells. If you are prescribed Protonix for long-term use, you may develop liver damage.You may also develop liver damage if you overdose on Protonix.
Protonix and Elevated Liver Enzymes
Protonix may cause elevated liver enzymes. Elevated liver enzymes indicate inflammation or damage to liver cells. When liver cells become irritated, they leak liver enzymes into the bloodstream, which can result in elevated liver enzymes on blood tests. If you have a history of liver disease, you should inform the doctor before Protonix is prescribed. The doctor may reduce your Protonix dosage and also request you to have regular blood tests.
Signs and Symptoms of Liver Damage
If you are taking Protonix, it is important to be aware of the signs and symptoms of liver damage. Signs and symptoms of liver damage include right-upper side abdominal pain, a swollen abdomen, dark urine, pale or clay-colored stool, itching, fatigue, fever, nausea, vomiting, weight loss, and yellowing of the eyes and skin. If you notice these symptoms, you should contact the doctor immediately. Long-term use of Protonix may cause cirrhosis or permanent scarring of the liver. A scarred liver cannot perform its functions, which leads to liver failure.
Protonix Administration
Protonix is available in form of delayed-release tablets and granules. The delayed-release tablets are usually taken once a day with or without food. The delayed-release suspension is usually taken 30 minutes before meals once or twice a day. If you have problems swallowing tablets, you may mix Protonix granules with applesauce and swallow immediately. Delayed-release tablets and granules should be swallowed whole without chewing or crushing to avoid releasing too much medication into the bloodstream.
Protonix Side Effects
If you are taking Protonix, you may experience common side effects such as nausea, stomach pain, vomiting, gas, bloating, dizziness, headache and joint pain, according to Drugs.com. These side effects should go way with continued use of Protonix. Adverse effects of Protonix include softening of bones, increased fractures, jerking muscle movements, muscle weakness and seizures.
