Zinc oxide is an ingredient commonly used in commercial lotions, ointments and creams design to treat minor skin conditions. Diaper creams, calamine lotion and hemorrhoid treatments contain zinc oxide. Certain types of paint and rubber products may also contain zinc oxide. Industrial sites that involve welding may expose you to zinc oxide in a gaseous form. An overdose of zinc oxide occurs when you ingest or inhale zinc oxide products in large doses.
Symptoms
Gastrointestinal distress is one of the primary symptoms you will encounter with a zinc oxide overdose. Abdominal pain, nausea, bloating, gas and diarrhea may occur. Fever and chills can also signify inappropriate exposure to the substance. Tingling or discomfort around the mouth and throat and coughing might also be expected. Some people who have experienced a zinc oxide overdose develop jaundice -- a yellowing of the skin and the whites of the eyes. Lethargy or a lack of awareness or consciousness can also be a symptom of overdose.
Home Treatment
Home treatment for a zinc oxide overdose varies according to the nature of the problem. If your eyes have been exposed to the cream, lotion or ointment, flush your eyes with cool water for at least 15 minutes. Inhaling the gas from the substance requires immediate removal to an outdoor area with plenty of fresh air. Drink a glass of water or milk if you have accidentally ingested a product containing zinc oxide and you are not vomiting or struggling to stay alert.
Medical Treatment
Medical treatment starts with calling the National Poison Control Center's toll-free number. If you are living in the United States, call 1-800-222-1222. Contact your local emergency service for assistance if you are outside of the United States. Experts in your situation will walk you through the process of home treatment and may tell you to seek additional medical help at a hospital or urgent care facility. Bring the zinc oxide product on which you overdosed with you and try to remember the time at which you ingested or inhaled the substance.
Metal Fume Fever
Metal fume fever is a rare but potentially serious condition that can occur after you have inhaled significant levels of zinc oxide. This condition is more likely to develop if your occupation is in the fields of welding, construction or foundry work. Symptoms are similar to that of an ingestion of zinc oxide, including fever, nausea and chills. You may also experience extreme fatigue, joint pain and muscle aches similar to the flu. The unique symptom associated with metal fume fever but not present in other forms of zinc oxide overdose is a metallic taste in the mouth. Shortness of breath and chest pain may follow within 12 hours of exposure. Continuous exposure to zinc oxide fumes over the course of several months can cause skin rashes and conjunctivitis. Treatment for metal fume fever includes rest, fever-reducing medication and pain relievers.
References
- MedlinePlus: Zinc Oxide Overdose
- "Journal of the Louisiana State Medical Society"; Metal Fume Fever: A Review of the Literature and Cases Reported to the Louisiana Poison Control Center; Syed Atif Ahsan, et al.; November/December 2009
- "Israeli Journal of Emergency Medicine"; Metal Fume Fever: An Uncommon Consequence of Inhalation Injury' A. Kurbaum, et al.; November 2007



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