Can You Overdose on Green Tea Extract?

Can You Overdose on Green Tea Extract?
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Green tea extract is taken for the potent antioxidants it contains. The antioxidants can protect the body from damage that may lead to cancer and other disease. In addition, green tea shows promise in promoting overall health and aiding in weight loss, longevity and disease treatment. Regardless, green tea is a potent stimulant and can have negative health effects if taken in large doses. Green tea may interfere with certain medications and medical conditions as well.

About Green Tea

Green tea comes from mature, unfermented leaves of the tea plant. Of all types of tea, green tea contains the highest concentration of antioxidants called polyphenols. Some research suggests that frequent green tea consumption may lower the risk of developing some cancers. Green tea may help lower cholesterol and prevent plaque from accumulating in arteries. Inflammatory bowel disease, liver disease and diabetes also show improved symptoms when green tea extract is taken.

Stimulant Mechanisms

Green tea contains stimulants such as caffeine, theobromine and theophylline. Even if green tea extract is decaffeinated, it can still be a potent stimulant. Polyphenols called catechin can inhibit the monoamine oxidase B enzyme in the brain, according to a 2010 study in the journal "Nutrition." MAO B is an important enzyme in the degradation of many neurotransmitters. Inhibition of MAO B can lead to an increased feeling of alertness but can cause a sharp rise in blood pressure if too much is taken. Too much green tea extract can cause irritability, insomnia, headache, rapid heart rate and dizziness.

Drug Interactions

Due to the MAO-inhibiting activity of green tea, it should not be taken with pharmaceutical inhibitors prescribed for depression. Green tea extract may also interfere with many other drugs given for neuropsychiatric disorders. Don't take green tea extract with blood thinners, as their effectiveness may be decreased. Over-the-counter cold medications containing phenolpropanolamine should not be taken with green tea extract.

Disease and Lifestyle Interactions

People with heart problems, kidney disease, stomach ulcers and neuropsychiatric disorders, in particular anxiety, should not take green tea extract. Avoid green tea extract if you take a large amount of other stimulants including caffeine. Consult with your doctor prior to taking green tea extract if you are under treatment for any other medical condition.

References

Article reviewed by Eric Lochridge Last updated on: May 30, 2011

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