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What Is L-Arginine HCL?

by
author image Joe King, M.S.
Joe King began writing fitness and nutrition articles in 2001 for the "Journal of Hyperplasia Research" and Champion Nutrition. As a personal trainer, he has been helping clients reach their fitness goals for more than a decade. King holds a Bachelor of Science in kinesiology from California State University, Hayward, and a Master of Science in exercise physiology from California State University, East Bay.
What Is L-Arginine HCL?
Arginine HCL is commonly used to promote blood and oxygen flow to muscles during exercise. Photo Credit Photodisc/Photodisc/Getty Images

Arginine is a non-essential amino acid that is important to may different bodily processes. Arginine HCL is a synthetically manufactured form of arginine that combines the amino acid with a hydrogen chloride molecule, and can be found in either powder or capsule form. It is used by athletes to increase oxygen delivery and blood flow during exercise, notes the book "Nutritional Supplements in Sports and Exercise." Hydrogen chloride is combined with arginine to make the supplement more palatable and to enhance its absorption by the digestive system.

Arginine HCL and Athletic Performance

One of the main effects of arginine is that it causes vasodilation, or an increase in the diameter of blood vessels. Arginine accomplishes this by stimulating the smooth muscle endothelial cells that line the blood vessels to produce a compound called nitric oxide. Nitric oxide stimulates blood vessels to relax and expand, increasing the flow of blood and oxygen to the muscles during bouts of intense exercise, especially resistance training. An increase in blood flow and oxygen delivery during exercise may enhance performance, allowing muscles to produce more strength and delaying the onset of exercise-induced fatigue.

Arginine HCL and Hormone Production

Arginine is an important catalyst for the production of human growth hormone, or HGH. When ingested, arginine HCL stimulates the anterior pituitary gland to release HGH, increasing plasma levels of HGH circulating throughout the body. Naturally elevated levels of HGH have many benefits, including an increase in muscle recovery and repair, regulation of metabolism, body fat reduction, and the optimal functioning of the heart and kidneys, according to "Nutritional Supplements in Sports and Exercise." Taking arginine in conjunction with other amino acids, specifically lysine and ornithine, may magnify this effect, the book's authors report.

Other Benefits of Arginine HCL

Arginine HCL may have a wide range of potential benefits beyond its use as a performance enhancer for athletes. MedlinePlus reports that possible benefits of arginine HCL supplementation include improving surgery recovery time, treating congestive heart failure, reducing chest pain in coronary artery disease, reducing bladder inflammation, treating erectile dysfunction, improving kidney function, and maintaining a healthy body weight in individuals suffering from muscle-wasting diseases such as HIV. Consult your physician before using arginine HCL as a treatment for any of these conditions.

Side Effects

Arginine HCL may have adverse effects on individuals who have liver and kidney disease, as well as on some individuals recovering from a heart attack. Arginine HCL may also upset the balance of potassium in the bloodstream. If you have a potassium deficiency, arginine may cause dehydration, nausea, stomach cramps and diarrhea. If you are taking blood thinner medications, arginine HCL supplementation may thin your blood even further, increasing your risk of impaired wound healing. Individuals with chronically low blood pressure are advised not to take arginine, as it may lower blood pressure even further, leading to fatigue and dizziness.

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