Folic acid is the synthetic form of the B-vitamin folate, which is found in supplements and fortified foods. You might require folic acid supplementation for a variety of purposes, including pregnancy, medications that lower levels of B-vitamin or due to the presence of certain medical problems. While folic acid supplements are generally safe, use could prove inappropriate in certain circumstances. If you believe taking folic acid will address a health concern you have, talk to your doctor about the appropriateness of using this supplement.
Masking B12 Deficiency
Taking folic acid supplements can correct certain problems associated with low levels of vitamin B12. However, this might be masking a deficiency of this vitamin, which can lead to serious, sometimes irreversible effects that folic acid will not address, such as nerve damage. Older individuals are more likely to have low B12 levels, and the National Institutes of Health Office of Dietary Supplements recommends anyone 50 and older get screened for B12 deficiency before taking folic acid supplements.
Side Effects
Folic acid can cause side effects in rare instances. Adverse reactions associated with this supplement include feelings of excitement or irritability, depression, sleep disturbances, bitter taste in the mouth, bloating, gas, nausea and loss of appetite.
Medication Interactions
Folic acid can reduce the absorption of the antibiotic tetracycline, which will reduce the effectiveness of the drug. You do not need to avoid folic acid supplements entirely, but you should take them and the medication at least a few hours apart. The NIH notes reports of folic acid triggering seizures in patients taking anticonvulsant drugs.
Conditions that Might Require Testing or Special Dosing for Safe Use
Like drugs, using natural supplements in the presence of certain medical problems could pose unique risks. Drugs.com reports having any of the following conditions might require special doses of folic acid and/or special tests to ensure safe use: alcoholism, infections, kidney disease and any form of anemia.
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