Buffalo fish is a type of freshwater fish that is best cooked in the oven. It isn't like buffalo-style chicken wings, served with ranch or blue cheese dressing for dipping. If that's disappointing to you, don't despair. You can still cook buffalo fish and baste the fish in creamy, buffalo-style hot sauce just like you do with chicken wings. Experiment with cooking buffalo fish, basting the fish with different ingredients.
Preheat the oven to 350 F.
Add the butter, pepper sauce, salt and vinegar to a saucepan to make the buffalo-style hot sauce for basting the fish. Place the pan on the stove and heat on medium-high setting until the butter melts. Remove it from the heat, and set it aside.
Place the buffalo fish fillets in a baking dish.
Baste the fish with the buffalo-style hot sauce, using a cooking brush. Put it in the oven, and bake it for 25 minutes.
Flip the fish fillets about 12 minutes into cooking with a spatula, basting the flipped size of the fish as well.
Remove the fish from the oven when the internal temperate reaches 145 F on a meat thermometer. The fish should also flake easily when punctured with a fork.