Aspartame is a chemical artificial sweetener that is widely used in diet and low-calorie foods and beverages. While the FDA has classified the use of aspartame as generally safe for human consumption, some people may develop an allergic reaction to the substance, leading to inflammation in soft tissues. If joint swelling and pain occur consistently after you consume products that contain aspartame, stop using the artificial sweetener and call your doctor.
Aspartame Allergy
As of 2011, the Asthma and Allergy Foundation of America states that while many claims have not been evaluated and verified, adverse reactions have been reported. Common reports claim that aspartame can lead to hives, headaches and swelling in the lips, hands and eyelids. The American Academy of Allergy, Asthma and Immunology explains that whenever a new chemical enters the body, there's a chance of developing an allergic reaction. This occurs if your immune system mistakes the chemical sweetener as a dangerous substance.
Joint Swelling
Joint swelling, pain and inflammation are commonly associated with food-related allergies, according to the Center for Food Allergies. During an allergic reaction, different chemicals are created that are intended to defend the body by attacking the aspartame. The presence of these chemicals causes inflammation in soft tissue, primarily because of the release of histamine. Histamine causes your blood vessels to dilate, leading to swelling. Soft tissues connect each joint in your body, which can become inflamed after consuming an allergen.
Clinical Diagnosis
To clinically diagnose your condition, you will need to make an appointment with an allergist. Concentrations of aspartame will be injected under your skin to observe how your body reacts to the substance. If your skin becomes red, swollen and inflamed within 20 minutes of the injection, you may need to undergo blood tests to confirm an allergy to aspartame. Blood tests will be sent to a lab that will look for the formation of immunoglobulin E antibodies when aspartame is added to your blood, according to the Center for Food Allergies.
Treatment
The only treatment for an allergy to aspartame is elimination of the substance from your diet. You may be able to use other artificial or natural zero-calorie sweeteners, such as stevia or sucralose. Before using these artificial sweeteners, talk with your doctor to ensure you're not allergic to these substances as well. If you accidentally ingest aspartame, oral antihistamines may help reduce your symptoms. If diagnosed with a severe allergy, you may be prescribed an epinephrine pen for use in case of an emergency.
