Seroquel, generically named quetiapine, is a prescription medication used to treat schizophrenia and bipolar disorder. Like other drugs, Seroquel can cause unwanted side effects in some users. Weight gain is common among Seroquel users and may increase the risk of diabetes. If you experience extreme weight changes while taking Seroquel, talk to your doctor. Together, you can determine a safe and effective dose of the medication.
Pharmacology
Seroquel is an atypical antipsychotic used to treat symptoms of depression, schizophrenia and bipolar disorder. It works by increasing levels of neurotransmitters that control mood and perception. Quetiapine -- the active ingredient in Seroquel -- is available in instant- and extended-release forms under the brand names Seroquel and Seroquel XR, respectively.
Side Effects
Weight gain is a typical side effect of Seroquel. According to EMedTV.com, approximately 23 percent of patients gained at least 7 percent of their body weight while taking the medication. In some cases, weight gain may be excessive, leading to an increased risk for diabetes. Seroquel is thought to cause weight gain by increasing appetite and causing sedation, which can discourage physical activity. Additional side effects may include dizziness, constipation, dry mouth, headache and indigestion, according to PubMed Health. In patients 24 years and younger, Seroquel may increase the risk of suicidal thoughts or behaviors.
Prevention/Solution
To prevent excessive weight gain while taking Seroquel, EMedTV suggests eating a heart-healthy diet and exercising for 30 minutes per day. Fresh fruits and vegetables, nuts, lean meats and low-fat dairy products are healthy choices for weight management. Limit your intake of sugar, saturated fat, trans fat, alcohol and cholesterol while taking Seroquel. Tell your doctor if you have a history of diabetes, heart disease or other chronic conditions. Contact your doctor at once if you experience worsening depression, suicidal thoughts, panic attacks or other troubling side effects while taking Seroquel. To prevent withdrawal-like symptoms, don't stop taking Seroquel abruptly without your doctor's supervision.
Considerations
Not everyone experiences weight gain or loss when taking Seroquel. Some of the conditions Seroquel is used to treat, such as depression, can cause weight changes. As depression symptoms remit, weight gain or loss may occur. Keep all appointments with your physician when taking Seroquel. Your doctor may weigh you regularly to monitor your health.



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