Oxalate salts are formed as a result of various metabolic processes in the body. They do not play any role in the body and are excreted via urine by the kidneys. Consuming large amounts of oxalate-rich foods such as green peppers, cucumbers, beer, chocolate milk and rhubarb may lead to increased amounts of oxalate in the urine. Oxalosis occurs when the kidneys fail completely. This leads to the accumulation of oxalate in the various organs of the body, causing complications such as anemia and skin ulcers. Nutrients such as vitamin C may increase the risk of oxalosis.
About Vitamin C
Vitamin C is a water-soluble vitamin important for growth and repair of various tissues in the body. It is also a powerful antioxidant and has the ability to stabilize free radicals formed as a result of various metabolic processes in the body. It is found in foods such as tomatoes, cantaloupes, citrus fruits and pineapple. Synthetic and natural vitamin C supplements are also available at most local pharmacies without a prescription. Your doctor may recommend them to treat several conditions including vitamin C deficiency, hypertension, diabetes, common cold and certain types of cancers. They are, however, associated with side effects such as upset stomach and diarrhea.
Link Between Vitamin C and Oxalosis
Vitamin C supplementation may increase the morbidity and mortality associated with chronic kidney diseases and increases the risk of oxalosis, according to a case study published in the August 2000 issue of the journal "Chest." Another study published in a 2006 edition of the journal "Kidney International" also suggests that vitamin C can be metabolized into oxalate salts and excess intake of the vitamin may increase the risk of oxalosis. The website Renal and Urology News reported in June 2009 that chronic kidney disease patients consuming more than 100 to 200 mg of vitamin C per day are at a greater risk of oxalosis.
Precautions
Although high doses vitamin C may lead to oxalosis, it also benefits kidney disease patients by preventing free radical damage and by increasing immunity. However, many patients do not get enough of this vitamin from diet as their doctors advise them to avoid fruits and vegetables due to their high potassium content. Hence, ask your doctor if a low dose of vitamin C supplement may be beneficial for you.
Other Supplements
Vitamin B-6 supplements, according to the University of Maryland Medical Center, may help treat elevated oxalate levels in the blood. Vitamin E supplements may also provide the antioxidant benefits similar to vitamin C. However, always talk to a doctor before using them.
References
- "Chest"; Acute Renal Failure, Oxalosis, and Vitamin C Supplementation* A Case Report and Review of the Literature; S. Mashour, et al.; August 2000
- "Kidney International"; Secondary Oxalosis Due to Excess Vitamin C Intake; S H Nasr, et al.; 2006
- Renal & Urology News: Vitamin C Supplementation and CKD
- University of Maryland Medical Center: Kidney Stones
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