Broccoli sprouts are rich in anticancer agents, with the main compounds being glucosinolates and isothiocyanates. A July 2003 trial conducted by the University of California, Davis, showed that phytochemicals found in broccoli sprouts offer protection against stomach cancer. Nonetheless, the case remains highly preliminary. If you have stomach cancer, talk to your doctor or registered dietitian for specific diet advice.
Antioxidant Property
Population studies show a correlation between high intakes of cruciferous vegetables such as broccoli and low incidence of stomach cancer, according to the University of Washington. Many investigators believe the damage caused by free radicals contributes towards the carcinogenic process. Broccoli sprouts naturally have a number of antioxidants that neutralize free radicals as they are produced during the body's normal chemical processes.
Helicobacter Pylori
Broccoli sprouts are an exceptionally rich source of inducers of enzymes such as sulforaphane, which are believed to aid in preventing stomach cancer. Sulforaphane blocks and kills precancerous cells, as well as fights against a bacterium called Helicobacter pylori that is found in the stomach and known to promote cancer there, researchers at the Johns Hopkins University School of Medicine report.
Conflicting Evidence
Sulforaphane has shown in-vitro activity against Helicobacter pylori, the University of Washington reports. Researchers examined the effect of sulforaphane in humans against this bacterium and found that H. pylori was not completely eradicated in patients who received 100 g of broccoli sprouts daily for two months. The result of this experiment suggests that sulforaphane may not be effective in the treatment of H. pylori-infected individuals.
Side Effects
Taking sulforaphane during pregnancy is possibly safe, states Oregon State University. No adverse effects or drug interactions have been reported with the use of sulforaphane or broccoli sprout extracts; however, sulforaphane may decrease the action of drug-metabolizing enzymes such as CYP enzymes. If you are taking prescription medications, you should talk to your doctor before you decide to use sulforaphane.
References
- University of California, Davis: Broccoli Could Cure Stomach Cancer; July 15, 2003
- University of Washington: Broccoli Sprouts, Cabbage, Ginkgo Biloba and Garlic: Grocery List for Cancer Prevention; Kathrynne Holden; Oct. 31, 2005
- Oregon State University; Linus Pauling Institute: Isothiocyanates; Jane Higdon; September 2005
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