Aloe vera is probably best known as a topical treatment for burns and other skin problems. It has also been consumed internally for a number of purposes, namely as a treatment for constipation. The Memorial Sloan Kettering Cancer Center notes studies of aloe suggest it might have immunomodulating and anticancer effects, but not enough evidence exists to confirm any therapeutic benefit. Several safety concerns surround consumption of aloe. If you believe consuming aloe juice will address a particular health concern, talk to your doctor about the appropriateness of its use.
Laxative Effect
Aloe juice and aloe resin both contain chemicals that exert a strong laxative effect by stimulating intestinal contractions to produce a bowel movement. Its mechanism of action can induce cramping and diarrhea. The Mayo Clinic notes that using it for more than seven days can result in your inability to have a bowel movement without the use of a laxative or worsening of your constipation. Many aloe juice products note that they are free of the resin -- where these chemicals concentrate strongly -- but since they exist in the actual juice as well, these problems are still a possibility. Do not consume aloe vera in any form if you suffer from inflammatory bowel disease, abdominal pain or intestinal obstructions or are experiencing episodes of nausea or vomiting.
Aloe's laxative properties could lead to low potassium levels, which can lead to a number of serious problems. This risk is particularly pronounced if you have heart, liver or kidney disease or take medications that lower potassium levels like certain types of diuretics or the heart medication digoxin.
Hypoglycemia
The Beth Israel Deaconess Medical Center notes that some studies suggest aloe might help lower blood sugar in type 2 diabetics. If it does work for this purpose, taking it at the same time as diabetes medications could result in hypoglycemia. When using natural therapies that act in a similar fashion as prescription drugs, you often need to adjust your medication dosages to compensate for this effect. Only your doctor can safely make these changes -- do not adjust your dosage of insulin or other blood sugar-lowering drugs on your own.
Use During Pregnancy or Breastfeeding
Drugs.com notes negative effects have been associated with internal aloe use in pregnant and breastfeeding women. It has abortifacient properties, meaning it could induce a miscarriage.
Other Safety Concerns
Do not give aloe juice to children. The Memorial Sloan Kettering Cancer Center notes the following adverse reactions have been reported: hepatitis, impaired thyroid function and bleeding while undergoing surgical procedures.
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