The root of the Amorphophallus konjac plant contains glucomannan, a substance that may work as a bulk-forming laxative. As a water-soluble dietary fiber, glucomannan creates larger, bulkier stool that moves through the colon more smoothly, requiring less pressure and straining to pass from the body. The Cleveland Clinic states although glucomannan has shown promise in clinical research studies, there's no definitive evidence that it is effective for constipation.
Uses
Glucomannan is primarily used to eliminate constipation. Clinical research studies found constipated participants taking glucomannan had bowel movements in as little as 12 hours, according to VitaGuide.org. Another usage for glucomannan involves lowering blood cholesterol levels. In fact, controlled and double-blind research trials have found supplementation with glucomannan significantly reduced total blood cholesterol, LDL cholesterol and triglycerides, according to PeaceHealth. In some research participants, glucomannan also raised HDL cholesterol, the "good" cholesterol. The Cleveland Clinic reports glucomannan also creates a feeling of fullness after consumption; therefore, researchers believe it may potentially be used as a weight loss supplement. However small, limited studies have been conducted in this area.
Preliminary Weight Loss Evidence
An eight-week double-blind trial entitled "Effects of Glucomannan on Obese Patients: A Clinic Study" was conducted to test purified glucomannan fiber as a food supplement in 20 obese patients, according to PubMed.gov. Research participants either received glucomannan or placebos. Glucomannan and placebos were given in 1 g doses, equal to two 500 mg capsules, with 8 oz. of water. Dosages were given to research participants approximately 1 hour prior to each meal, consisting of breakfast, lunch and dinner. Results showed a significant reduction in weight loss, roughly 5.5 lbs., in participants given glucomannan during the eight-week period.
Dosage
When taking glucomannan for laxative purposes, you should consume 3 to 4 g per day, according to PeaceHealth. If you are trying to lower blood cholesterol levels, take anywhere from 4 to 13 g per day. For weight loss purposes, 1 to 3 g before each meal has shown to be effective in clinical research. PeaceHealth reports despite the reason for using glucomannan, all users should start with a small amount and increase gradually. Additionally, you should drink at least 8 oz. of water each time you take glucomannan.
Warnings
According to the Cleveland Clinic, glucomannan tablets are not considered safe since they may cause blockages of the throat or intestines. In fact, several countries have banned glucomannan due to its high incidence of gastrointestinal obstruction. Glucomannan can also interfere with blood sugar control, and therefore blood sugar should be closely monitored if you have diabetes. The Cleveland Clinic actually recommends diabetics to avoid taking glucomannan due to its influence on blood sugar levels.
References
- VitaGuide.org; Glucomannan; 2011
- PeaceHealth; Glucomannan; December 23, 2009
- Cleveland Clinic; Stay Fit; Over-the-Counter and Herbal Remedies for Weight Loss; March 24, 2010
- PubMed.gov; Effects of Glucomannan on Obese Patients: A Clinical Study; 1984
- Cleveland Clinic; Herbal Remedies for Weight Loss?; 1995-2011



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