Depression is a common complication of pregnancy, often caused by a combination of hormonal factors and environmental stressors. Untreated pregnancy-related depression can jeopardize the health of the expectant mother or her unborn child. Although some women may be interested in using naturopathic treatments, such as 5-HTP, to treat this pregnancy-related mood disturbances, there is not enough evidence to recommend 5-HTP during pregnancy. In theory, it could cause serious complications to the mother or child.
5-HTP Explained
5-HTP, or 5-hydroxytryptophan, is a chemical byproduct produced when the human body metabolizes tryptophan, an amino acid. Although 5-HTP is not found in appreciable amounts in any foods, its precursor, tryptophan, occurs naturally and necessarily in the human diet. The University of Maryland Medical Centers notes that 5-HTP alters levels of serotonin, a neurotransmitter involved in mood regulation and several bodily functions. Supplements containing 5-HTP may help treat conditions marked by serotonin-related medical conditions.
Possible Uses
Emerging scientific evidence suggests that 5-HTP can help ease the symptoms of several medical conditions, but there isn't yet enough evidence to prove that the benefits are worth the potential risks. While MedlinePlus advises not using this supplement until more studies are done, it rates 5-HTP as "possibly effective" as a treatment for depression and fibromyalgia, noting that there is not enough evidence to rate its effectiveness for other conditions including anxiety, weight loss, PMS and sleep disorders.
Dangers in Pregnancy
During pregnancy, medicinal compounds can readily cross through the placenta, leading to side effects in the unborn baby. Other products trigger uterine contractions, increasing the chances of preterm birth and miscarriage. No studies have investigated the rates of pregnancy complications among women taking 5-HTP. Both MedlinePlus and University of Maryland Medical Center strongly urge expectant mothers to avoid the supplement. Consult your health care provider before taking 5-HTP during any stage of life.
Treatment Alternatives
There are several safe, proven treatment options available to pregnant women with depression. The American Pregnancy Association recommends support groups, private psychotherapy, and "light" therapy to women suffering from mild to moderate depression during pregnancy. In cases when depression is severe or disabling, a health care provider may recommend medication. He can carefully weigh the benefits and risks of each treatment option to ensure the continued health of both the mother and child.
Member Comments