Progesterone pills contain the hormone progestin, according to the Mayo Clinic. They can be prescribed for a number of reasons for both men and women. Such uses include preventing pregnancy, treating endometriosis or treating appetite reduction or severe muscle and weight loss in patients with acquired immunodeficiency syndrome (AIDS) in men and women. As with any medication, progesterone pills have the potential for side effects.
Common Side Effects
As reported by Drugs.com, the most commonly occurring side effects of using progesterone pills are not considered serious unless they become persistent or bothersome. These side effects include bloating, tenderness of the breasts, diarrhea, dizziness, drowsiness, dry mouth, fluid retention, headache, heartburn, irritability, pain in the muscles, nausea, abdominal pain or cramping, tiredness and/or vomiting.
Serious Side Effects
Individuals who experience any serious side effects should report them to their doctor immediately. Drugs.com suggests the following as serious side effects of progesterone pills: unusual vaginal bleeding, eye bulging, coughing up of blood, darkened urine, double vision, fainting, gallstones, mood changes, mental changes, migraine, numbness of an arm or leg, pain in the breasts, lumps in the breasts, weakness on one side of the body, chest pounding, seizures, tremors, severe abdominal pain, speech difficulties, swelling, severe headache, sudden onset of severe vomiting, dizziness or yellowing of the skin or eyes. The Mayo Clinic suggests that other hazards with progesterone pill use include appetite changes, skin rash, frequent urination or unusual thirst.
Allergic Reaction
Some individuals may experience a severe allergic reaction to progesterone pills. Drugs.com reports the symptoms of this to be hives, rash, itching, trouble breathing, chest tightening, swelling of the mouth, swelling of the lips, swelling of the tongue or swelling of the face.


