Glucosamine comprises a major component of cartilage, which cushions the joints. For this reason, it is a popular supplement for treating arthritis. The University of Maryland Medical Center notes studies examining this benefit have produced mixed results, however. This supplement might also address other conditions, but not enough evidence exists to draw any firm conclusions. Some dosage guidelines exist based on research, but you should check with your doctor about an appropriate dose for your needs.
Arthritis Dose
The University of Pittsburgh Medical Center notes a suggested dosage of 1,500 mg daily for treating arthritis. You can take this in one dose or divide it into three doses of 500 mg each.
Dose for Other Conditions
Limited research suggests glucosamine might prove effective for other conditions. The University of Michigan Health System recommends the following specific doses for certain conditions. For brittle nails, for example, try 1,500 mg a day; diarrhea in autistic children, 250 mg with morning and evening meals; rheumatoid arthritis, 1,500 mg; and sprains and strains; 750 to 1,500 mg.
Length of Use
The University of Michigan Health System stresses that glucosamine cannot cure arthritis and to maintain benefits, you might require the supplement for the rest of your life. It states one trial, which lasted for three years, suggests glucosamine is safe for long-term use.
As for any other conditions, check with your doctor about how long you can use glucosamine and if you would require dosage adjustments for prolonged supplementation.
Considerations
The Memorial Sloan Kettering Cancer Center reports glucosamine supplements might affect glucose metabolism and how well your body uses insulin. If you have diabetes, you might require increases in your medication dosages to compensate for this interference. Do not make these adjustments on your own. Talk to your doctor about the appropriateness of using glucosamine supplements in this instance. It might also interact with anticoagulant medications.
Glucosamine sulfate supplements might have high levels of potassium and sodium. This could prove problematic in certain instances, such as having kidney disease or taking medications like potassium-sparing diuretics. If you need to restrict these nutrients for any reason, you might consider using another form of glucosamine.



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