Selenium sulfide is an anti-infective agent that is used to relieve itching and flaking of your skin, particularly your scalp. Selenium sulfide is commonly found in a lotion and is applied to the scalp as a shampoo for several weeks or until the skin infection or dandruff is gone. As with any topical medication that is applied to your skin, certain precautions should be taken to avoid potential harmful effects related to its use. Consult your physician before using a shampoo or cream containing selenium sulfide.
Allergic Reaction
Some individuals may experience an allergic reaction to selenium sulfide. An allergic reaction to the active ingredients, such as the element selenium, may cause both internal and external symptoms of an allergic reaction due to your body's ability to absorb selenium into your bloodstream through your skin. Common symptoms of an allergic reaction to selenium sulfide include the appearance of a rash or hives, increased sweating, difficulty breathing, and an irregular heartbeat.
Side Effects
According to the "National Library of Medicine," the use of selenium sulfide can cause common side effects that are usually mild. These side effects include oiliness or dryness of your hair and scalp, hair loss, hair discoloration, scalp irritation, and skin irritation. If you experience scalp or skin irritation, it could be the sign of a more serious side effect, such as an allergy, and it is recommended that you consult your physician or seek medical attention immediately.
Toxicity
According to the EWG Cosmetic's Database, selenium sulfide is highly toxic and is considered to be a neurotoxin when ingested. Selenium sulfide is classified as a human carcinogen, or a cancer-causing substance. Oral ingestion of selenium sulfide can increase your risk of developing certain cancers as well as increase your risk for developing upper respiratory infections. If you accidentally ingest selenium sulfide, rinse your mouth out with water and seek medical attention immediately.
Other Precautions
According to Drugs.com, you should avoid using other similar topical medications for the treatment of dandruff while also using selenium sulfide. Other skin medications may hinder the absorption and effectiveness of selenium sulfide. As a potential skin irritant, avoid getting selenium sulfide into any open orifice, including your eyes, nose, and mouth. It is not recommended to use selenium sulfide on sunburned, windburned, dry, chapped or broken skin.
References
- Pub Med Health; Selenium Sulfide; 2008
- "The New Encyclopedia of Vitamins, Minerals, Supplements and Herbs"; Nicola Reavley; 1999
- "National Library of Medicine"; Selenium Sulfide; 2008
- EWG.org; Selenium Sulfide
- Drugs.com; Selenium Sulfide Topical; 2010


