Antidepressant medications work in a variety of ways to boost the performance of neurotransmitters, the natural chemicals in your brain that support normal brain function. Lexapro is the brand name for one type of antidepressant. Although Lexapro may cause certain side effects, there is no evidence that this drug can affect your cholesterol levels.
Cholesterol
Standard cholesterol tests measure two types of cholesterol in your blood stream, as well as your total cholesterol amount. LDL cholesterol refers to low-density lipoproteins, the type of cholesterol that delivers this waxy substance throughout your cells and tissues. An excess amount of LDL cholesterol can build up in your blood vessels, restricting the flow of blood and increasing your risk of circulatory problems. HDL cholesterol, or high-density lipoproteins, acts as scavengers by transporting the excess cholesterol out of your bloodstream. An HDL level of 60 mg/dl or higher is desirable for most men and women.
Lexapro
Escitalopram is the antidepressant drug that goes by the brand name of Lexapro. This medication is a type of selective serotonin reuptake inhibitor, or SSRI. Antidepressant drugs within this class work by increasing the serotonin in your brain. The possible side effects of Lexapro do not include changes to cholesterol levels, although this medication may lead to insomnia, nausea, drowsiness and sweating. It can also cause difficulties in achieving orgasms and result in a decreased libido.
SNRIs
Serotonin and norepinephrine reuptake inhibitors, or SNRIs, are a separate class of antidepressants that include duloxetine and venlafaxine. Unlike Lexapro, these antidepressants may cause an increase in cholesterol levels. SNRIs can also cause other side effects, such as anxiety, weight loss, increased heart rate and tiredness.
Considerations
Although SNRIs can affect your cholesterol levels, they are less likely to interfere with certain medications. Do not take Lexapro if you take pimozide, citalopram or monoamine oxidase inhibitors. Even though Lexapro may not help increase your level of healthy HDL cholesterol, you can boost these beneficial lipoproteins by making some lifestyle changes that include losing weight, getting more physical activity and choosing healthier sources of fats, such as olive oil and canola oil. Eliminating cigarettes and restricting your alcohol consumption may also help improve your cholesterol levels.
