You may think you're doing your body good by ingesting artificial sweeteners because they don't contain any calories, but some artificial ingredients, such as aspartame, may trigger adverse reactions. Digestive symptoms typically develop first because the digestive tract is the first system to come in direct contact with the ingredient. Aspartame has been under controversy for decades and has not been resolved. If you suspect that ingesting aspartame causes stomach pain, stop consuming the substance and call your doctor.
Controversy
Artificial sweeteners come under severe scrutiny in the 1970s when certain tests performed on lab rats connected some artificial sweeteners with the development of cancer. Since then, almost every artificial sweetener has been under attack. According to the Mayo Clinic, each artificial sweetener, including aspartame, must undergo various tests before it can be approved by the Food and Drug Administration for use in foods and beverages. The FDA has approved the use of aspartame as generally safe when consumed in limited quantities. As with any substance, you can develop intolerance or an allergic reaction to aspartame.
Intolerance
It's not clear how many people have aspartame intolerance, but the Asthma and Allergy Foundation of America states that common side effects of aspartame intolerance include hives, headaches, swelling of the eyelids and stomach pain. These symptoms remain as claims because they have not been scientifically proven in lab tests. An intolerance occurs when the substance triggers an uncommon chemical reaction in the body that could cause inflammation, irritation and swelling in various parts of your body. Intolerance is not the same condition as an allergic reaction.
Allergic Reaction
An allergic reaction can occur with any substance you ingest. If you're allergic to aspartame, your immune system identifies the chemical as a dangerous invader that poses a threat to the body. The American Academy of Allergy, Asthma and Immunology states that the immune system creates immunoglobulin E antibodies to attack the aspartame to rid from the body. The introduction of IgE antibodies into the bloodstream begins a chain reaction that releases histamine and other inflammatory chemicals. The lining of your stomach becoming inflamed can lead to stomach pain, cramping, nausea and diarrhea.
Testing
If your doctor suspects that you have an allergy to aspartame, she may recommend allergy testing. A small amount of aspartame is injected under your skin to see whether your skin becomes inflamed, turns red or forms bumps. If your skin reacts, your doctor will confirm the production of IgE antibodies with a blood test.


