The blossoms of the red clover plant have been used for centuries in naturopathic medicine. Red clover blossoms contain compounds similar to the human reproductive hormone estrogen. Because of its estrogenic properties, red clover has been investigated as a treatment for menopausal complaint and menstrual disorders. However, its capacity to influence reproductive hormones renders it inappropriate for pregnant and nursing women.
Hormonal Effects
According to the University of Maryland Medical Center, red clover contains isoflavones, which are hormone-like compounds chemically and structurally similar to the hormone estrogen. Estrogen governs several functions within the female body, including fertility, sexual health, pregnancy and breast-feeding. These hormone-like compounds are capable of influencing the human endocrine system, particularly when used in large doses. Isoflavones are responsible for many of the side effects associated with red clover, as well as many of its reputed medicinal benefits.
Benefits
In theory, red clover's hormonal effects could benefit people with hormone-related disorders. MedlinePlus acknowledges red clover's popularity as a treatment for menopausal complaints, breast pain and premenstrual syndrome, or PMS. In theory, red clover could also offer benefits for fertility and pregnancy, since estrogen governs conception and the progression of pregnancy. However, MedlinePlus reports that there is insufficient evidence to recommend the use of red clover in any medicinal capacity.
Risks to Pregnancy
MedlinePlus regards red clover as "likely unsafe" when taken in medicinal doses during pregnancy. Because red clover can behave like estrogen and cause imbalances in the reproductive hormones involved in pregnancy, healthcare providers speculate that it could cause serious side effects to pregnant women and their unborn babies. The herb could lead to serious pregnancy complications, such as miscarriage, pre-term birth and birth defects. The University of Maryland Medical Center also reports that red clover can reduce fertility in animals. In theory, these effects could also apply to humans.
General Side Effects
Red clover can cause several unpleasant side effects that are not specific to pregnancy. According to the University of Maryland Medical Center, the most common side effects of red clover supplements include headache, nausea and rash. In addition, MedlinePlus warns that the herb can cause vaginal spotting, which can be a serious concern during pregnancy. Nevertheless, the University of Maryland Medical Center reports that serious side effects have not been reported for pregnant, healthy women using the herb as recommended.



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