Is Valerian Root Safe to Take With Buspar?

Is Valerian Root Safe to Take With Buspar?
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Since the second century, people have used the herbal remedy Valerian root to treat insomnia, anxiety and nervous disorders. Available in capsules, tinctures and tea, Valerian root doesn't require a prescription. BuSpar is a prescription medication used to treat anxiety. You shouldn't take two different substances designed to treat the same symptoms without your doctor's permission. Doing so could lead to serious side effects.

Valerian and Anxiety

The United States Food and Drug Administration classifies Valerian as "generally recognized as safe." Its effects are generally mild; some people may notice no effect at all, though it may become more effective if you take it for several weeks. Scientists believe Valerian increases the amount of gamma aminobutyric acid, or GABA, in the brain. This is similar to the action of other anti-anxiety drugs, including benzodiazepines, such as diazepam, which is sold under the brand name Valium, or alprazolam, sold as Xanax. Valerian's effect is much milder than these prescription drugs. For anxiety, the recommended dosage is 200 mg, three to four times daily.

BuSpar and Anxiety

Buspirone, the active ingredient in BuSpar, doesn't work like benzodiazepines or Valerian. It acts on your brain's dopamine and serotonin receptors to reduce anxiety. Doctors use BuSpar to treat mild to moderate anxiety. You may need to take the drug for several weeks before you enjoy its full effect. BuSpar can cause dizziness or drowsiness, especially when you first begin taking the drug. These side effects should resolve as your body adjusts to the medication. BuSpar is available as 5-, 10-, 15- and 30-mg tablets.

BuSpar and Valerian

BuSpar can increase the effect of sedatives and other anxiety drugs. Since Valerian can be both a sedative and a treatment for anxiety, BuSpar could increase this effect, which could be dangerous. If you're taking BuSpar for anxiety, you shouldn't take Valerian at the same time. If BuSpar isn't controlling your anxiety symptoms, you may need a different medication. If you want to take Valerian because you're having trouble sleeping, consult your doctor first to make sure it's safe.

Precautions

Don't give Valerian to children without checking first with your physician. Don't take Valerian if you are pregnant. If you experience a rash, swelling or other signs of an allergic reaction with either BuSpar or Valerian, stop taking the medication and contact your doctor. Be sure to let your doctor know about any other drugs or herbal remedies you take, including Valerian, since the herb may interact not only with BuSpar, but with other medications.

References

Article reviewed by MER Last updated on: Jul 17, 2011

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