Antidiabetic Activity of Andrographis Paniculata

Antidiabetic Activity of Andrographis Paniculata
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Andrographis paniculata, or Indian gentian, is an Asian herb traditionally used to treat malaria, cardiac conditions, fever, chronic liver problems and infectious diseases, notes Deepak Chopra, M.D., in his 2000 book, "The Chopra Center Herbal Handbook." If you have diabetes, you might be interested to know that as of 2011, scientists were researching Andrographis's ability to lower blood sugar. If you want to take Andrographis, it is important to fully inform your doctor about any supplements that you are taking.

Andrographis Paniculata

Also known as the "king of bitters," Andrographis is an annual plant that flourishes on the east Indian flatlands. It bears dainty lavender or pink flowers and seeded fruits, and the entire plant is utilized as a botanical remedy. Among its plant chemicals are flavonoids, or pigments that also can offer you antioxidant effects. The herb's primary bioactive compounds are called andrographolides, which are believed to have a stimulating effect on your immune system, writes Chopra. Use Andrographis under the supervision of a qualified medical professional.

Diabetes

According to the National Diabetes Information Clearinghouse, or NDIC, almost 2 million new cases of adult diabetes were diagnosed in 2010. NDIC estimates more than 25 million Americans have the disease, which includes seven million undiagnosed cases. Self-management strategies are an important part of handling the complications and emotional stress of diabetes. These include exercise, proper diet, blood sugar monitoring and preventative care of your body's vulnerable areas, such as your feet, teeth and eyes. Diabetes can lead to chronic damage of your heart, kidneys, and other organs. Additionally, it is the primary cause of new adult blindness cases in the United States, reports the NDIC.

Research Studies

Clinical studies of Andrographis have revealed the herb's ability to combat bacteria, ulcers, viruses, inflammation, pain and high blood pressure, according to the Memorial Sloan-Kettering Cancer Center. In a 2000 study published in "Clinical and Experimental Pharmacology and Physiology," researchers tested an ethanol extract of Andrographis on normal and diabetic mice. Their results showed the plant extract lowered the animals' blood sugar levels and may act as an antioxidant, as well. Consult a qualified health care professional if you think you may have diabetes.

Safety and Considerations

Andrographis can cause side effects such as exhaustion, queasiness, headache and diarrhea, cautions MSKCC. Incidents of a life-threatening condition called anaphylactic shock have been noted after ingestion of the herb. Symptoms of anaphylactic shock include wheezing, dizziness, skin rashes or hives and trouble breathing. In addition, Andrographis can potentially interact with other medications, such as cancer and blood-thinning drugs.

References

Article reviewed by GlennK Last updated on: Jul 20, 2011

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