Autism spectrum disorder is a range of neurological disorders with symptoms such as impaired social interaction, communication difficulties and repetitive movements. Autism can range from a mild dysfunction to a severe impairment. The exact cause of autism is not known but a genetic component seems to be involved. Treatment for autism varies depending on the symptoms, but behavioral interventions are generally used along with vitamins, medications and changes in diet.
Vitamin B6 and Magnesium
High doses of combined vitamin B-6 and magnesium is one of the most well-researched treatments for autism. Doctors believe that children with autism have a difficult time breaking down B-6. People with autism also appear to have a significantly lower level of magnesium. Although numerous studies suggest that this combined therapy can be effective in treating autism, many of the studies were flawed in their design. Two well-controlled studies demonstrated no positive or negative effects of taking vitamin B-6 and magnesium on the symptoms of autism, according to a research review conducted by C. Nye and A. Brice published in the "Cochrane Library."
Omega-3 Fatty Acids
Omega-3 fatty acids are essential for human health; however, these necessary supplements can be obtained only through diet. Omega-3 fatty acids concentrate in the brain and aid in cognitive and behavioral functioning. Extensive research has been conducted to test whether omega-3s can help relieve symptoms of autism. Although many studies suggest that these supplements can help, a systematic review of clinical studies published in the "Journal of Autism and Developmental Disorders" in 2009 found insufficient scientific evidence to determine if omega-3s are effective in treating autism.
Probiotics
Some children with autism have an extremely low level of beneficial bacteria in their stomach and a high level of harmful bacteria leading to gastrointestinal symptoms. Harmful bacteria can also reduce cognitive functioning. A study on giving children with autism probiotics conducted by Reading University was allegedly stopped because of a high drop-out rate. The blind study involved 40 autistic children, half of whom were given the probiotic bacteria L. The other half received a placebo. According to Professor Glenn Gibson, who led the study, the control group dropped out during the study. The results of the study, reported in 2006, were inconclusive.
Medications
Certain medications are prescribed to children with autism depending on their symptoms. Anti-psychotic medications may be used to control irritability and anger outbursts. The United States Food and Drug Administration approved risperidone, an anti-psychotic, for the treatment of irritability in children and teenagers with autism. Another anti-psychotic, aripiprazole, has also been approved by the FDA in the treatment of autism. The drug is effective in reducing aggression and self-injurious behavior in children with autism. Some anxiety medication is used to treat any compulsive symptoms associated with autism.
References
- National Institute of Neurological Disorders and Stroke: Autism Fact Sheet
- Autism-Society; Summary of Biomedical Treatments for Autism; James B. Adams
- Journal of Autism and Developmental Disorders; Omega-3 Fatty Acids for Autistic Spectrum Disorder: A Systematic Review; Stephen Bent, et al.; August 2009
- The Cochrane Journal Club; Combined Vitamin B6-Magnesium Treatment in Autism Spectrum Disorder (Review); C. Nye, et al.; 2009
- Autism-Nutrition: Probiotics for Autism
- U.S. Food and Drug Administration; FDA Approves the First Drug to Treat Irritability Associated with Autism, Risperdal; October 2006



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