Does Trazodone Alter Cholesterol?

Does Trazodone Alter Cholesterol?
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Trazodone is a prescription medication used to treat psychological conditions such as depression and other off-label conditions like insomnia. Like most medications, Trazodone can cause side effects, particularly if you have just begun to take the medication. Over time, many side effects should subside. Some side effects however, may continue while you are taking this medication and can pose an increased risk of illnesses like cardiovascular disease. Never start, stop or adjust a medication dosage without first consulting your doctor.

Trazodone

Trazodone is a type of antidepressant medication that increases the amount of serotonin in your brain and body. This medication is also used to treat symptoms of schizophrenia, as well as insomnia and anxiety. Patients are usually started on a small dosage of Trazodone which is gradually increased until a therapeutic effect is achieved. The minimum amount of time to achieve an effect is two weeks, so you may still experience symptoms for which you are being prescribed this medication.

Cholesterol

Cholesterol is a waxy substance that is naturally made by your body and also comes from certain foods you eat. Cholesterol comes in one of two basic types. HDL, or "good" cholesterol, helps to prevent LDL or "bad" cholesterol from attaching to the walls of your arteries. This is why it's important to know not only your total blood cholesterol, but your HDL and LDL levels too. An HDL under 40 mg/dL for men and under 50 mg/dL in women is cause for concern because it indicates an increased risk of cardiovascular disease.

Trazodone and Cholesterol

Trazodone appears to have an effect on total cholesterol levels but in a relatively unique way. A 1990 study published in "Therapeutic Drug Monitoring" found that several antidepressant medications, including Trazodone, actually lowered total cholesterol levels in all of the participants in the study. Additionally, the website Drugs.com explains that Trazodone may have fewer negative cardiovascular effects than other antidepressants. It, too, lists reduced serum cholesterol as a potential side effect of Trazodone.

Considerations

High cholesterol is associated with an increased risk of a heart attack, stroke and high blood pressure. Fortunately, it appears that the medication Trazodone does not increase cholesterol levels and in fact, may lower total cholesterol. Regardless of the medication you take, always get regular blood tests and monitor your total, HDL and LDL cholesterol levels. If necessary, your primary physician can administer other medications to lower high cholesterol. Be sure to mention any supplements including herbs and over the counter medications you are taking to your physician so that you provide a complete picture, helping prevent unwanted interactions.

References

Article reviewed by David Fisher Last updated on: Jul 22, 2011

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