Breast cancer is a type of cancer that begins in the breast tissue. Your age, family history, menstruation pattern, alcohol, radiation and hormone replacement therapy increase the risk of the condition. Symptoms include a lump in the breast; changes in size, color or shape of breast; bone pain; breast pain; weight loss; and skin ulcers. The treatment generally includes chemotherapy, radiation therapy and medications. Certain supplements such as zinc might also play an important role in pathophysiology and management of breast cancer.
About Zinc
Zinc is an essential trace element that plays an important role in the proper functioning of the immune system, growth, development, reproduction and thyroid function. It also possesses significant antioxidant functions that help stabilize free radicals formed as a result of various metabolic activities in the body. The mineral can be obtained from foods such as red meat, poultry, legumes, lima beans, whole grains and sunflower seeds. Your doctor might also recommend zinc supplements to treat a variety of conditions, including acne, macular degeneration, colds, stomach ulcers and infections. The dose depends on age and condition of the patient.
Link Between Zinc and Breast Cancer
Zinc might help reduce certain side effects associated with radiation therapy, including mouth sores and loss of taste, according to the American Cancer Society. It also boosts the immune system and might help fight secondary infections in cancer patients. However, a study in the June 2009 issue of the journal "Genes and Nutrition" suggests that imbalance in zinc metabolism in the breast tissue during and after lactation might contribute to the transition and progression of breast cancer. Another study published in the August 2007 issue of the journal "Cancer Epidemiology, Biomarkers and Prevention" says elevated levels of zinc in the breast tissue might increase the risk of breast cancer.
Side Effects
Zinc supplements are associated with other side effects as well, including nausea, vomiting, upset stomach and metallic taste. High doses of the supplement can also lead to loss of muscle coordination, hallucinations and anemia, and can interfere with certain antibiotics and anti-inflammatory and blood pressure medications.
Precautions
As the role of zinc in breast cancer is unclear, it is important to talk to a doctor before using zinc supplements. Tell your doctor about your pre-existing conditions and medications you are taking to help make an informed decision.
References
- "Genes and Nutrition"; "Mammary Gland Zinc Metabolism: Regulation and Dysregulation"; Shannon Kelleher et al.; June 2009
- "Cancer Epidemiology, Biomarkers and Prevention"; "Levels of Zinc, Selenium, Calcium and Iron in Benign Breast Tissue and Risk of Subsequent Breast Cancer"; Yan Cui et al.; August 2007
- Cancer.org: Zinc
- University of Maryland Medical Center: Zinc
