Lipitor, also known as atorvastatin, is a popular cholesterol-lowering medication. Although it is effective, Lipitor has many side effects, some more serious than others. Grapefruit offers several benefits but may pose a health risk when combined with Lipitor. Understanding how this medication and fruit work both separately and together is key to preventing life-threatening complications.
Lipitor
Lipitor, a statin, lowers cholesterol by slowing its production in the liver. It is one of the more popular drugs in this class, and its doses range from 5 to 80 mg. The higher your cholesterol, the higher your dose. Joint and muscle aches are the most common side effects and often subside once your body acclimates to the drug. In rare instances, muscle myopathy develops. This is severe muscle and joint pain and tenderness, which may lead to rhabdomyolysis, a rare but life-threatening condition resulting in muscle breakdown, explains MayoClinic.com.
Grapefruit
Grapefruit, a member of the citrus family, can interact adversely with certain medications, such as Lipitor. Your body breaks down and processes the medication you take, ensuring proper function. The chemicals in grapefruit prevent the enzymes responsible for this process from taking place, resulting in higher levels of these medications in your body, explains FamilyDoctor.org. This can increase your risk of experiencing the side effects of these medications. Any grapefruit product can interact adversely with Lipitor, including grapefruit juice and supplements.
Alternative Medications
If grapefruit is part of your daily diet, and you cannot imagine life without it, you have options. The American Academy of Family Physicians reports you can safely take other statins, such as Lescol, Pravachol and Crestor, and still enjoy grapefruit products. Zocor, however, interacts negatively with grapefruit and its products. Additional cholesterol medications, such as bile acid sequestrants, niacin and fibric acids are safe for you to take as well.
Considerations
Even the smallest amount of grapefruit products can cause a negative reaction with Lipitor, and it can take up to three days for this reaction to occur. Beware of pomello and seville oranges, which may have the same effect as grapefruits. Other fruits, including those in the citrus family, are safe to consume. There is no proof to show they interact with medications, according to FamilyDoctor.org. If you choose to enjoy an occasional glass of grapefruit juice while taking Lipitor and notice an increase in joint or muscle pain, notify your doctor immediately. Muscle myopathy and rhabdomyolysis can lead to kidney failure.
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