Pills that combine many vitamins together called multivitamins, are sold as over-the-counter dietary supplements. Some people take multivitamins as part of a healthy daily routine, while others need to take these vitamins to help meet the recommended daily vitamin requirements. People who take multivitamins may experience side effects such as headache, stomach upset or nausea.
Side Effects
The most common side effects of taking multivitamins are upset stomach, strange taste in the mouth, headache and nausea. Some people experience nausea when taking multivitamins on an empty stomach or when taking multivitamins that contain high iron content such as prenatal vitamins. Taking large amounts of iron may cause constipation in some, which in turn leads to stomach upset or nausea.
Alternatives
Drugs.com recommends that you take your multivitamin with a glass of water or juice to minimize nausea or upset stomach. Some people may experience heartburn or acid reflux after swallowing large multivitamin tablets. David Katz, M.D., stated in the December 2000 issue of "O Magazine" that swallowing large multivitamins may irritate the esophagus and trigger acid reflux in some people.
Considerations
If your multivitamin causes you to become nauseous, bloated, constipated or have other stomach problems, consult with your physician about changing your brand of multivitamin. You can also look into trying different forms of multivitamin such as liquid or powder, which may be easier on your digestive system, since it will have less to break down. Do not take laxatives while taking your multivitamin without consulting your pharmacist or physician, as these medications may inhibit the absorption of certain vitamins.
Warnings
If you develop symptoms such as nausea, vomiting, diarrhea, constipation or severe abdominal cramping after taking too many multivitamin supplements, contact poison control. These are symptoms of hypervitaminosis and mineral poisoning, which are both medical emergencies.



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