zig
0

Notifications

  • You're all caught up!

Recommended Dosage of Pregnenolone

by
author image Janet Renee, MS, RD
Janet Renee is a clinical dietitian with a special interest in weight management, sports dietetics, medical nutrition therapy and diet trends. She earned her Master of Science in nutrition from the University of Chicago and has contributed to health and wellness magazines, including Prevention, Self, Shape and Cooking Light.
Recommended Dosage of Pregnenolone
Pregnenolone is used for hot flashes. Photo Credit Hemera Technologies/AbleStock.com/Getty Images

Pregnenolone is a powerful hormone. It does not occur naturally in your diet. Your body generally makes enough pregnenolone to meet your needs, under normal circumstances. However, pregnenolone levels decline with age. Pregnenolone is available as a dietary supplement in doses ranging from 5 mg to 50 mg. There is no standard dose. As with any supplement, take pregnenolone only under your doctor's supervision.

Significance

Your adrenal glands produce pregnenolone -- a steroid hormone -- from cholesterol. Steroid hormones exert a wide variety of physiological effects. Pregnenolone is known as the grandmother hormone, due to its role in producing other steroid hormones. It is a precursor to the primary sex hormones testosterone, progesterone and estrogen. It is also a precursor to other steroid hormones including aldosterone, which controls sodium and potassium balance, and cortisone, your body's primary stress hormone.

Typical Dosage

Pregnenolone as a dietary supplement is marketed for memory, mental energy and mental clarity. Though there is no standard dose, it is typically taken at 30 mg daily. In clinical settings, pregnenolone is typically prescribed at 100 mg daily and used to treat clinical deficiencies. In research settings, doses up to 700 mg are reported. You should take pregnenolone in the dose your doctor determines is beneficial for your individual circumstances.

Uses

Pregnenolone is used primarily to treat deficiencies because of conditions such as adrenal insufficiency, which is when the adrenal glands fail to produce enough hormones. As a supplement, pregnenolone is used to combat stress, fatigue and menopausal symptoms, and for brain enhancement. However, human studies to support these uses are lacking.

Precautions

Your endocrine system helps your body maintain a delicate hormonal balance. Too little or too much hormone can have adverse health effects. Taking pregnenolone in the absence of a clinical deficiency may disturb your endocrine function. Pregnenolone may also interact with other drugs. It can decrease the effectiveness of a sedative drug class known as benzodiazepine, which includes Valium and Xanax. Ask your doctor before taking any supplements, and tell him if you are taking any other supplements or medicines.

LiveStrong Calorie Tracker
THE LIVESTRONG.COM MyPlate Nutrition, Workouts & Tips
GOAL
  • Gain 2 pounds per week
  • Gain 1.5 pounds per week
  • Gain 1 pound per week
  • Gain 0.5 pound per week
  • Maintain my current weight
  • Lose 0.5 pound per week
  • Lose 1 pound per week
  • Lose 1.5 pounds per week
  • Lose 2 pounds per week
GENDER
  • Female
  • Male
lbs.
ft. in.

YOU MIGHT ALSO LIKE

CURRENTLY TRENDING

Demand Media

Our Privacy Policy has been updated. Please take a moment and read it here.