Vitamins may play a role in helping to relieve some of the symptoms associated with Cushing's disease. A rare disease of the endocrine system, Cushing's is caused by a pituitary tumor that leads to the production of excessive amounts of cortisol, a steroid hormone secreted in the adrenal glands. Because Cushing's disease affects the complicated balance of the endocrine system as well as disturbs neurological, skeletal and muscular function, it is important to consult a physician prior to taking a nutritional supplement or making significant dietary changes.
Symptoms of Cushing's Disease
The symptoms associated with Cushing's disease are caused by exposure to abnormally high levels of cortisol. Cushing's disease is commonly marked by the growth of a fatty mound between the shoulder blades, obesity in the upper body and severe facial swelling and reddening. In most instances, Cushing's disease also results in dermatological problems, such as an increased susceptibility to acne and skin infections, skin that bruises easily and purple stretch marks across the thighs, breasts and stomach. Cushing's disease typically leads to muscle weakness and a loss in muscle mass, as well as a decrease in bone density. Additionally, patients with Cushing's disease often test positive for lower-than-normal potassium levels.
Vitamins to Support Cushing's Disease
While as of 2011 there is not sufficient evidence to suggest that supplemental vitamins or diet will aid in the treatment of Cushing's disease, nutritional support may help reduce the severity of associated symptoms. Specifically, vitamins to aid in immune function, skin tissue repair and bone health may prove beneficial for some Cushing's disease patients to support bone strength and dermatological health. However, in the absence of validated medical research, it is important to maintain a well-balanced diet that ensures an adequate supply of nutrients obtained from a variety of wholesome sources. According to the National Institutes of Health, the relationship between diet and well-being may be especially critical for people with Cushing's disease.
Vitamins for Skin Health
The skin ailments that accompany Cushing's disease may benefit from the inclusion of vitamins E and C in the diet. Vitamin E is a fat-soluble nutrient and antioxidant that helps protect the cells, tissues and organs from the harms of free radicals. Vitamin E supports the strength of the immune system and aids in the repair of skin tissue. Vitamin E may also reduce the appearance of stretch marks and help calm inflammation associated with acne. Vitamin C, also an antioxidant, is used for the growth and repair of all tissues and cells in the body, and forms part of the protein that makes up skin. Vitamin C aids in healing wounds, and additionally helps to maintain cartilage and bones.
Vitamins for Bone Health
Calcium and vitamin D may help support the bone health of Cushing's disease patients. In addition to its role in cell growth, immune function and the reduction of inflammation, vitamin D is vital for maintaining healthy bones. Deficiencies in vitamin D can result in bones becoming thin and brittle and increase the risk for osteoporosis. Vitamin D is also required for the absorption of calcium, which is necessary to form strong bones and increase bone mass.
References
- National Endocrine and Metabolic Diseases Information Service; Cushing's Syndrome; July 2008
- Warren Grant Magnuson Clinical Center: Nutrition for Patients with Cushing Syndrome
- Linus Pauling Institute; Vitamin E; Jane Higdon, Ph.D.; November 2004
- MedlinePlus: Vitamin C
- Office of Dietary Supplements: Vitamin D
- Centers for Disease Control and Prevention: Calcium and Bone Health
