Zinc is the second highest occurring trace mineral in your body, next to iron, according to the University of Maryland Medical Center. Found in every cell in your body, zinc plays an important role in maintaining your overall health. Researchers have varying opinions of the interaction between folic acid and zinc, with previous research suggesting high folic acid intake adversely affects zinc absorption in your body. A research study published in the January 1995 issue of "The Journal of Nutrition" suggests that this may not be the case.
Zinc
Zinc is an essential trace mineral that supports numerous functions in your body. Important for reproduction, growth and taste, zinc also supports the functioning of your immune system. The antioxidant properties of this mineral protect your body from the damaging effects of free radicals. Zinc plays a role in insulin and thyroid function, as well as blood clotting.
Folic Acid
Folic acid, the synthetic form of vitamin B-9, is one of eight B vitamins responsible for converting food into fuel for your body. It is a water-soluble vitamin, meaning that your body doesn't store folic acid. These vitamins support the growth of healthy hair, eyes, skin and liver. Vitamin B-9 is an important vitamin for the brain, supporting emotional and mental health.
B-9 and Zinc
The Linus Pauling Institute advises "the bioavailability of dietary folate is increased by the action of a zinc-dependent enzyme, suggesting a possible interaction between zinc and folic acid." The institute further advises that some studies have demonstrated low zinc intake decreases folate absorption, while other research shows folic acid supplementation decreases your ability to utilize zinc. However, a January 1995 study published in "The Journal of Nutrition" found that high doses of folic acid did not impair zinc absorption, and zinc did not adversely impact folate utilization.
Cautions
Both vitamin B-9 and zinc may interact with other medications or supplements you are taking, so review with your doctor prior to using either supplement. Zinc may interact with antibiotics, diuretics and blood pressure pills. Folic acid may mask symptoms of vitamin B-12 deficiency and may interact with tetracycline. Side effects may occur when taking any supplement. Folic acid produces side effects rarely, usually in the form of stomach and sleep problems. Seizures are also a reported side effect. Zinc may produce dizziness, stomach upset and a metallic taste in your mouth.
References
- University of Maryland Medical Center: Zinc
- Drugs.com: Vitamin B Complex/Vitamin C/FolicAcid/Iron/Zinc
- University of Maryland Medical Center: Vitamin B-9
- "Nutrition Research Newsletter"; Interactions Between Folic Acid and Zinc; April 1995
- Linus Pauling Institute; Zinc; Jane Higdon, Ph.D.; December 2003
- "The Journal of Nutrition"; Zinc Status Is Not Adversely Affected by Folic Acid Supplementation and Zinc Intake Does Not Impair Folate Utilization in Human Subjects; G.P Kauwell, et al.; January 1995
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