Phosphatidylcholine & Inflammation

Phosphatidylcholine is a phospholipid that may decrease inflammation in the body. A reduction in inflammation would not only be beneficial to the treatment of inflammatory diseases such as rheumatoid arthritis, but also in the prevention of conditions such as cancer and ulcerative colitis. Studies have examined the relationship between phosphatidylcholine and inflammation, and many have found positive results. Speak with your doctor about whether or not a supplement such as phosphatidylcholine could be right for you.

Phosphatidylcholine

According to "Body Bio Bulletin", phosphatidylcholine is the most important phospholipid in your body; phospholipids are a type of fat molecule that makes up approximately half of your cell's membranes. As such, it helps to transmit nerve signals, and can also be used as a concentrated energy source. Scientists believe it may be helpful in a number of conditions, including multiple sclerosis, psoriasis, atherosclerosis and malnutrition. It is found naturally in certain foods that are high in fat, including egg yolk and soy. Additionally, it is available as an intravenous treatment and in the form of lecithin -- a substance isolated from egg yolk that contains phosphatidylcholine and is able to be given as a supplement or added to foods.

Phosphotidylcholine and Inflammation

A study published in the 2007 issue of the "The Journal of Biological Chemistry" looked at the effects of supplemented phosphatidylcholine on inflammation in cells. The scientists found that when added to cells, phosphatidylcholine inhibited pro-inflammatory processes. Another study published in the 2009 edition of "Arthritis Research and Therapy" examined the relationship of phosphatidylcholine on inflammatory symptoms of study participants who had rheumatoid arthritis-like symptoms induced by injection. The results of the study showed that when pretreated with phosphatidylcholine, levels of inflammation were diminished.

Dosing

Phosphatidylcholine is available as a capsule or injection. It is also available in the form of lecithin, which contains approximately 10 to 20 percent phosphatidylcholine. Dosages can range from 300 to 1,000 mg two to three times a day depending upon your medical condition. Follow the bottle for dosing instructions, or speak with your doctor about what dose would be appropriate for you.

Considerations

Phosphatidylcholine and lecithin are generally considered safe; only minor negative side effects, such as nausea or diarrhea have been seen. Before taking phosphatidylcholine, lecithin, or any other supplement, speak with your doctor about whether it is right for you. Tell your doctor about any medications or supplements you are taking, as he may need to change them. Additionally, your medical and nutritional status should be monitored while taking phosphatidylcholine to ensure that you are not experiencing negative effects.

Phosphatidylcholine & Inflammation