If you've been prescribed warfarin, also known as Coumadin, to reduce your risk for blood clots, you should be aware of possible interactions. Although licorice may bring to mind long, red pieces of chewy candy, it's actually a plant with many uses, and it can interfere with warfarin's effectiveness. If you're taking warfarin, you should be cautious with licorice and products that contain it and talk to your doctor.
About Warfarin
Warfarin is prescribed for patients with heart-related problems, including previous heart attack or an irregular heart beat, to reduce the risk of blood clotting. It's classified as a blood-thinner because it reduces the likelihood of clotting, effectively helping to "thin" the blood. Warfarin is taken as a pill and your doctor will monitor your intake and dosage closely. Common side effects include gas, fatigue and increased feeling of cold sensation.
Licorice Basics
Licorice plants are used to flavor candy, foods, beverages and tobacco, and it's root is used in some medications. Some shampoos to reduce oily hair also contain licorice. It's purported uses vary widely from heartburn to infertility to muscle cramps. However, it's considered an alternative treatment and not specifically approved for any condition. According to MedlinePlus, it's likely safe when consumed in foods, but be cautious if taking licorice in large amounts for four weeks or more.
Licorice and Warfarin
Licorice may reduce warfarin's effectiveness and may increase your chances for clotting. It may interact with warfarin by accelerating the body's breakdown and removal of the medication. Look at product labels to see if you're consuming or using any products that may contain licorice, and then consult your doctor about it. You may be advised to discontinue licorice intake while you're taking warfarin to ensure the drug works optimally.
Other Possible Interactions
Warfarin requires close monitoring of vitamin K intake. Consuming vitamin K, found in large quantities in green, leafy vegetables such as kale and spinach, should remain moderate and consistent on a daily basis while taking warfarin. If vitamin K levels vary too much, the drug won't work properly. Cranberries, soybean and canola oils may also affect warfarin's effectiveness. Licorice also interacts with many other medications besides warfarin. Heart-related drugs, such as digoxin, estrogen medications, corticosteroids and blood pressure medications, may interact with licorice and negatively impact the drug's intended use. Talk to your doctor if you're combining licorice with any other medications.



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