Retin-A (tretinoin) cream is a prescription topical treatment for acne. It is usually applied to affected areas of the face one time per day, prior to bedtime. It is best to wash your face with a mild soap, pat it dry, and then wait 30 minutes before applying Retin-A. The U.S. Food and Drug Administration notes that results can be seen in 3 weeks, though more than 6 weeks of application may be necessary before results are seen. If you use Retin-A, it is safe to use cosmetics, as long as the cream is cleansed from your face prior to applying any makeup.
Skin Side Effects
The most common side effects of Retin-A are burning, stinging, itching, dryness and peeling of the skin. This happens particularly during the first few weeks of treatment and usually improves by about 4 weeks into treatment. Retin-A can make you more sensitive to sunlight, according to the FDA. While on this medication, it is best to avoid direct exposure to sun and consistently use sun screen. Your doctor can recommend what level of SPF sunscreen you should use. Some people who have used Retin-A report increased pigment in their skin, but this side effect went away when treatment was discontinued. Call your doctor immediately if your face becomes very dry, swollen, red, blistered or your skin becomes crusty.
Eye Side Effects
Use of Retin-A cream near the eye can cause temporary stinging of the eye and sometimes a mild turning outward of the edge of the eyelid. Call your doctor if you experience persistent eye redness or watering, or eye lid swelling.
Liver Side Effects
Liver side effects have been noted in some patients who use Retin-A. These side effects are mild and reversible, and include: increased levels of bilirubin and the enzymes glutamic-oxaloacetic transaminase, alkaline phosphatase and glutamic-pyruvic transaminase.
Allergic Reaction
RxList.com reports that a very serious allergic reaction to this drug is unlikely, but signs of such a reaction include: rash, swelling, severe dizziness, trouble breathing, or itching.
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