Metoprolol is a prescription beta blocker medication used to control high blood pressure and prevent angina. Taken after a recent heart attack, it improves chances of survival. Doctors also prescribe extended-release metoprolol with other medications to treat congestive heart failure. L-arginine is an amino acid you can buy over the counter. Research indicates it also may have some benefits for cardiovascular conditions, reports MedlinePlus. Talk to your doctor before you combine metoprolol and L-arginine.
Function
Like other beta blockers, metoprolol relaxes and widens blood vessels by blocking the hormone epinephrine, also called adrenaline. In addition, metoprolol slows the heart rate and allows the heart to beat with less force. These effects improve blood flow and reduce blood pressure. L-arginine works differently; the body converts it to nitric oxide, which causes blood vessels to widen.
L-Arginine Cardiovascular Benefits
Taking L-arginine supplements in addition to conventional medication for congestive heart failure seems to help reduce fluid retention, according to MedlinePlus. L-arginine supplements also appear to reduce symptoms of angina, and to increase exercise capacity and quality of life in people with this condition. In addition, this amino acid may be effective for reducing leg pain and weakness caused by blocked arteries.
Considerations
Research is insufficient to evaluate whether taking L-arginine is helpful for reducing blood pressure, concludes MedlinePlus. It may lower blood pressure slightly in people who don't have hypertension and in Type 2 diabetics with mild high blood pressure. Unlike metoprolol, L-arginine apparently is not beneficial for patients who have recently experienced a heart attack, and it actually may have harmful effects.
Interaction
Although research has not confirmed whether L-arginine supplements cause significant reductions in blood pressure, notes MedlinePlus, blood pressure could drop too low if these supplements are combined with medications that treat hypertension. MedlinePlus characterizes this as a major interaction and discourages combining metoprolol and L-arginine supplements. Low blood pressure can cause dizziness, lightheadedness and fainting. Consult your doctor before taking L-arginine supplements if you have a cardiovascular condition, particularly if you take metoprolol or any other medication.
Member Comments