The amino acid tyrosine naturally occurs in many foods, and your body can also make it from another amino acid, phenylalanine. A deficiency is rare, and you would be unlikely to require a supplement for this purpose. Tyromine's role in creating brain chemicals that impact mood suggest it might have a role in treating depression and other mood disorders such as stress. Not enough evidence exists to make any firm conclusions, however. Tyromine supplements do not have clear-cut dosing guidelines, and you should talk to your doctor about the right dose for your needs.
Safe Upper Limit
Many drugs and supplements have a known safe, upper limit, and using more than this amount has documented adverse effects. This information is not available for tyrosine, but this does not mean it does not potentially have a safe maximum dose. Some dosing guidelines exist based on professional recommendation and research, and they can serve as a guideline.Taking four times the recommended amount does not necessarily mean you will reap benefits four times greater. Because the suggested dose can vary depending on the condition, it is important to get professional guidance regarding how much to take and for how long.
Dose Guidelines
Studies have used anywhere from 7 to 30 g daily in studies, according to the Beth Israel Deaconess Medical Center. This does not mean you should just take 30 g because it has been used before. The University of Michigan Health System reports the following doses were used in studies for specific conditions: stress: 150 mg for every 2.2 lbs of body weight; depression: 100 mg for every 2.2 lbs; Parkinson's disease: 45 mg per 2.2 lbs.
Many health professionals recommend 500 to 1,000 mg three times a day, according to the University of Maryland Medical Center.
Considerations for Long-Term Use
Michigan Health System reports a lack of significant side effects associated with tyromine supplements. It also notes, however, limited information regarding the safety of long-term use, particularly when taking it in doses of several grams daily. While it is always important to consult with your doctor, it is particularly important to receive his guidance about the dose and other aspects of safe use if you plan on using this supplement for months at a time or longer as the length of treatment might influence how much you should be taking.
Other Considerations for Use
Tyromine supplements might worsen hyperthyroidism and trigger migraine headaches in susceptible individuals. Never use any supplement without your doctor's OK if you have liver or kidney disease. Using tyrosine along with MAO inhibitors, a type of antidepressant, may cause dangerously high blood pressure that can increase your risk for heart attack or stroke.
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