According to Drugs.com, misoprostol is a medication used to prevent the development of ulcers in the stomach from the use of anti-inflammatory drugs, such as aspirin. The medication works by reducing the amount of acid produced by the stomach and helps it protect itself from acid damage, as indicated by Drugs.com. As with any medication, misoprostol has the risk of side effects.
Most Common Side Effects
According to Drugs.com, the most common side effects associated with the use of misoprostol may include abdominal pain or diarrhea. These effects are considered harmless unless they become persistent or overly bothersome. The Physicians' Desktop Reference reports that some individuals may experience some of the mild side effects for the first few weeks of treatment only. These should disappear as the body gets used to the drug, usually within eight days.
Less Common or Rare Side Effects
Patients who experience side effects considered to be rare or less common should report the issue to a doctor. Such effects include bleeding from the vagina, constipation, cramps in the lower abdomen, gas, headache, heartburn, indigestion, nausea or vomiting. The Physicians' Desktop Reference suggests women may experience light bleeding between menstrual periods, heavier bleeding during menstruation or excessive menstrual pain or cramps. Other side effects may include paleness, stomach bleeding or intestinal bleeding, as indicated by the Physicians' Desktop Reference.
Other Serious Concerns
Drugs.com lists several side effects of an overdose that are considered to be dangerous. These include convulsions, diarrhea, drowsiness, pounding heartbeat, rapid heart rate, fever, reduced blood pressure, slowed heartbeat, tremor or difficulty breathing. An allergic reaction is possible with the use of misoprostol. Signs of such a reaction include hives, trouble breathing and/or swelling of the face, throat, tongue or mouth.



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