Ciprofloxacin, often called Cipro, is a fluoroquinolone antibiotic. It works by killing bacteria that cause infections. Cipro has an interaction with caffeine that calls for some caution when consuming food, beverages or medications that contain caffeine. Cipro also interacts with several other common substances. Ask your doctor about combining caffeine with this antibiotic and about any other interactions as well.
Function
Ciprofloxacin is effective against a wide range of microorganisms, such as species of staphylococcus and streptococcus. It can be used to treat bacterial skin infections, certain types of pneumonia, urinary tract infections, gonorrhea, E. coli infections, salmonella and dysentery. Doctors also prescribe Cipro to treat cases of anthrax or to prevent the infection in people who may have been exposed to these bacteria.
Caution
Ciprofloxacin can make the effects of caffeine stronger. This doesn't mean you have to give up your coffee or cola while taking Cipro, but you might want to drink less of it, particularly until you determine whether you experience any increased caffeine effects. Excess caffeine effects can include nervousness, anxiety, irritability, jittery sensations, heart pounding, upset stomach and sleep problems.
Interaction
A study published in the April 1989 issue of "Antimicrobial Agents and Chemotherapy" describes the method in which Ciprofloxacin interacts with caffeine. Cipro appears to impair the body's ability to metabolize and remove caffeine, thus significantly increasing the length of time caffeine remains in the body and increasing the concentration of caffeine.
Prevention
Caffeine occurs in or is added to regular coffee, black and green tea, energy drinks, cola and some other soft drinks and chocolate. Some medications, such as certain pain relievers and non-drowsy cold medications, contain caffeine. You may need to limit or avoid use of these substances while taking Cipro. The antibiotic interacts with numerous other substances as well. Calcium, for instance, can inhibit the absorption of Cipro, which makes taking Cipro with dairy products or calcium-fortified juice a problem. It's OK to consume the two at the same time if you're eating a full meal, according to MedlinePlus. Otherwise, take the medication several hours before or after consuming calcium. Cipro also interacts with aluminum and magnesium. Tell your doctor about any supplements or any antacids you take before beginning Cipro therapy.
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